In Bangladesh, serological tests have been widely used for the primary screening of visceral leishmaniasis (VL). Several serologic tests are available for the diagnosis of VL. Selection of the best test is important to permit diagnostic differentiation between symptomatic and asymptomatic patients and to reduce cross-reactivity. We evaluated the effectiveness of a new serological test “Onsite Leishmania Ab Rapid Test” as a part of “quality assurance” activities for the kala azar elimination programme of the Government of Bangladesh. Plasma samples of 100 parasitologically confirmed cases of VL along with 101 healthy controls were tested, and “Onsite Leishmania Ab Rapid Test” strip tests were positive in 94 out of 100 confirmed VL cases, whereas four out of 51 healthy subjects from the VL endemic areas also tested positive. All the 50 healthy volunteers tested negative. Thus, the sensitivity and specificity of “Onsite Leishmania Ab Rapid Test” strip test were found to be 94% (95% CI: 87–98) and 96% (95% CI: 90–99), respectively. This study showed that the performance of the “Onsite Leishmania Ab Rapid Test” strip tests was up to the recommended level.
This paper presents how a post-secondary institution like University of British Columbia’s Okanagan (UBCO) campus can reduce its carbon footprint and be aligned with the government’s target through promoting virtual campus and autonomous electric vehicles (AEVs). Different virtual campus scenarios are developed: online classes only, working-from-home only, and a hybrid of both. In the case of AEVs, alternative penetration rates for levels 2 and 5 are considered. A total of 50 scenarios are tested using a sub-area transport simulation model for UBCO, which is extracted from the regional travel demand forecasting model. The results suggest that a 40% AEV penetration rate coupled with fully in-person classes reduces GHG by ~36% compared to the 2018-level, which will help UBCO to achieve their 2030 emission reduction target and be aligned with the provincial target. The 50% AEV and 10% hybrid virtual campus reduces emissions by ~48%, which is aligned with the 2040 provincial target. A fully virtual campus will help to reach the 2050 provincial target by reducing GHG by ~76%. The results further demonstrate that level 5 AEVs produce lesser emissions than level 2 at a lower AEV penetration rate for the fully in-person campus scenario. At higher penetration rates, level 5 performs better only if it is coupled with 10% of students, faculties and staffs attending virtual campus scenario.
Road safety research in developing countries has evolved in two categories: (a) crash frequency prediction modeling and (b) injury severity analysis. In injury severity analysis, the focus is to identify the influential factors for different injury severity categories. However, limited research has been undertaken in this domain, especially to assess the injury severity of the occupants of unconventional vehicles (UVOs) (including both human-pulled and engine-operated vehicles). This study investigates the injury severity of UVOs in Dhaka, Bangladesh adopting a hybrid of latent segments and random parameters logit (LSRPL) models. The model is developed utilizing police-reported collision records for the years 2011–2015. The LSRPL model captures multi-dimensional heterogeneity by allocating victims into discrete latent segments (i.e., inter-segment heterogeneity) and allowing a continuous distribution of parameters within the segments (i.e., intra-segment heterogeneity). The model is estimated for two segments using victim and crash attributes, where segment one is lower risk and segment two is higher risk. The model results suggest that victim and driver profiles, crash attributes, environmental factors, road network attributes, transportation infrastructure, and land use attributes influence the injury severity of UVOs. The model confirms the existence of significant inter-segment heterogeneity. For example, mid-block crashes are more likely to result in severe injury in higher-risk segments, and less likely to result in severe injury in lower-risk segments. The model further confirms intra-segment heterogeneity for areas with higher levels of mixed land use. For example, for mid-block crashes, higher mixed land use shows a significantly lower mean in high-risk segments, revealing lower likelihood of sustaining severe injury.
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