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Oxidative stress is associated with many acute and chronic inflammatory diseases, yet limited treatment is currently available clinically. The development of enzyme-mimicking nanomaterials (nanozymes) with good reactive oxygen species (ROS) scavenging ability and biocompatibility is a promising way for the treatment of ROS-related inflammation. Herein we report a simple and efficient one-step development of ultrasmall Cu5.4O nanoparticles (Cu5.4O USNPs) with multiple enzyme-mimicking and broad-spectrum ROS scavenging ability for the treatment of ROS-related diseases. Cu5.4O USNPs simultaneously possessing catalase-, superoxide dismutase-, and glutathione peroxidase-mimicking enzyme properties exhibit cytoprotective effects against ROS-mediated damage at extremely low dosage and significantly improve treatment outcomes in acute kidney injury, acute liver injury and wound healing. Meanwhile, the ultrasmall size of Cu5.4O USNPs enables rapid renal clearance of the nanomaterial, guaranteeing the biocompatibility. The protective effect and good biocompatibility of Cu5.4O USNPs will facilitate clinical treatment of ROS-related diseases and enable the development of next-generation nanozymes.

The intrinsic electronic properties of donor (D) and acceptor (A) materials in coupling with morphological features dictate the output in organic solar cells (OSCs). New physical properties of intimate eutectic mixing are used in nonfullerene‐acceptor‐based D–A1–A2 ternary blends to fine‐tune the bulk heterojunction thin film morphology as well as their electronic properties. With enhanced thin film crystallinity and improved carrier transport, a significant JSC amplification is achieved due to the formation of eutectic fibrillar lamellae and reduced defects state density. Material wise, aligned cascading energy levels with much larger driving force, and suppressed recombination channels confirm efficient charge transfer and transport, enabling an improved power conversion efficiency (PCE) of 17.84%. These results reveal the importance of utilizing specific material interactions to control the crystalline habit in blended films to form a well‐suited morphology in guiding superior performances, which is of high demand in the next episode of OSC fabrication toward 20% PCE.

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Symmetric-breaking strategy has broadly applied in organic photovoltaic material design while a comprehensive understanding of the effects of two dimension (2D) asymmetric side chains in all-small-molecule organic solar cells (ASM-OSCs)...

Visible-near infrared photodetectors are reported with excellent overall device parameters from conjugated polymers with different optical bandgaps by optimal design in device structure and optimizing the thickness of the photoactive layer in nanoscale. The best visible-near infrared photodetectors show high detectivity (D*) of 1.7 × 10(13) Jones at a wavelength of 710 nm, which is among one of the best results of polymer photodetectors reported to date.

Objective: The objective of this study was to analyze the 100 most cited studies on vaccine. Methods: A comprehensive search of studies on vaccine was performed in the Web of Science Core Collection without year or language restrictions. The 100 top-cited studies were retrieved after screening abstracts or full-texts. The outcomes of bibliometric analysis included citation time, citation density, journal name, impact factor, publication year, article type, category, open access, and country of origin. Results: The citation times for the 100 top-cited studies ranged from 593 to 2406, with a median citation times of 834. The 100 top-cited studies were published in 32 journals, and the journal with the most studies was New England Journal of Medicine (n = 20). They were published between 1969 and 2012, and 4 authors published at least 2 studies as the first author. The USA contributed the most studies (n = 70), followed by Switzerland (n = 4), England (n = 4) and Finland (n = 4). Eighty-one studies were published as Article, while 19 were Review. Eleven studies were about vaccine for therapeutic and 68 studies were about vaccine for prophylactic. Conclusions: This is the first bibliometric analysis to provide a detailed list of the 100 most-cited studies on vaccine and helps to recognize the quality of the works, discoveries, and trends in the field.