IntroductionTo investigate whether respiratory variation of inferior vena cava diameter (cIVC) predict fluid responsiveness in spontaneously breathing patients with acute circulatory failure (ACF).MethodsForty patients with ACF and spontaneous breathing were included. Response to fluid challenge was defined as a 15% increase of subaortic velocity time index (VTI) measured by transthoracic echocardiography. Inferior vena cava diameters were recorded by a subcostal view using M Mode. The cIVC was calculated as follows: (Dmax - Dmin/Dmax) × 100 and then receiver operating characteristic (ROC) curves were generated for cIVC, baseline VTI, E wave velocity, E/A and E/Ea ratios.ResultsAmong 40 included patients, 20 (50%) were responders (R). The causes of ACF were sepsis (n = 24), haemorrhage (n = 11), and dehydration (n = 5). The area under the ROC curve for cIVC was 0.77 (95% CI: 0.60-0.88). The best cutoff value was 40% (Se = 70%, Sp = 80%). The AUC of the ROC curves for baseline E wave velocity, VTI, E/A ratio, E/Ea ratio were 0.83 (95% CI: 0.68-0.93), 0.78 (95% CI: 0.61-0.88), 0.76 (95% CI: 0.59-0.89), 0.58 (95% CI: 0.41-0.75), respectively. The differences between AUC the ROC curves for cIVC and baseline E wave velocity, baseline VTI, baseline E/A ratio, and baseline E/Ea ratio were not statistically different (p = 0.46, p = 0.99, p = 1.00, p = 0.26, respectively).ConclusionIn spontaneously breathing patients with ACF, high cIVC values (>40%) are usually associated with fluid responsiveness while low values (< 40%) do not exclude fluid responsiveness.
At the bedside, clinical guidelines are fully applied in 24% of patients. Our study underlines the need to both improve the process of implementation and become cognizant of excessive proliferation of clinical guidelines.
In summary, only 56.6% of ICU patients receiving SAT had CP. Most strains were susceptible to SAT. A similar 28-day mortality rate was observed among groups; the late administration of SAT significantly worsened the prognosis of patients with less severe CP.
RésuméObjectif La prise en charge des patientes pré-éclamptiques sévères est un défi pour les équipes travaillant en secteur obstétrical. Nous montrons ici que l'échographie de plusieurs organes du corps réalisée au lit d'une patiente a apporté des informations nécessaires à la prise en charge, sans nécessité de la transférer en service de radiologie ni d'avoir recours à des intervenants extérieurs. É léments cliniques Une patiente pré-éclamptique sévère de 29 ans avec un HELLP syndrome (hémolyse, cytolyse, thrombopénie) développe en post-partum une hémorragie utérine occulte diagnostiquée grâce à une échographie abdomino-pelvienne réalisée au chevet. L'échoguidage a aussi simplifié la mise en place d'un abord veineux central. Cette patiente évolue favorablement après une hystérectomie d'hémostase et l'administration de facteur VII activé. Les échographies pulmonaire et cardiaque ont optimisé la prise en charge hémodynamique non invasive de cette patiente ayant développé un choc hémorragique puis un oedème pulmonaire. L'échocardiographie a guidé le remplissage vasculaire et l'échographie pulmonaire a permis de détecter l'apparition de l'oedème pulmonaire interstitiel et d'en suivre l'évolution. Conclusion Les praticiens doivent être informés de l'intérêt de l'échographie du « corps entier » dans le diagnostic et le traitement de pathologies complexes impliquant plusieurs organes, comme la pré-éclampsie. De plus, l'échographie facilite la prise en charge de l'hémodynamie globale. La formation des anesthésiologistes aux différentes techniques échographiques devrait être encouragée.
AbstractPurpose Management of severe pre-eclamptic patients is a challenge for the staff on obstetrical wards. We demonstrate that ultrasound applied to several organs performed at a patient's bedside gave the information required for the patient's management, without the need to transfer her to the radiology department or to call external consultants. Clinical features A 29-yr-old severely pre-eclamptic patient with HELLP syndrome (hemolysis, cytolysis, thrombopenia) presented, in the post-partum period, with an occult uterine hemorrhage diagnosed with bedside abdominal/pelvic ultrasound. Ultrasound was also used to insert a central venous catheter. After undergoing a
The major finding of the present study is the existence of a gap between the widely approved EoL recommendations made by scientific societies and the daily practice of southern French ICUs. Even if EoL decisions are mostly shared with relatives, their written documentation in medical charts remains insufficient. Concerning EoL practices, the withdrawal of treatment remains an uncommon decision.
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