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The proposed framework allows (1) the authoring and (2) the verification of clinical guidelines against specific requirements defined based on a set of property specification patterns, enabling non-experts to easily write formal specifications and thus easing the verification process.

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Highlights• We provide a unified taxonomy for KPIs management that gathers any relevant aspect highlighted by the literature.• We rigorously apply a methodology for taxonomy development in the Information Systems field.• The taxonomy defines a five-based dimension comparison including around 21 different aspects.• We provide the reader with a complete and consistent background of KPIsbased concepts.• We provide a comprehensive comparison of the proposed taxonomy with other similar works. AbstractIn recent years, research on Key Performance Indicators (KPIs) management has grown exponentially, giving rise to a multitude of heterogeneous approaches addressing any aspect concerning it. In this paper, we plot the landscape of published works related with KPIs management, organizing and synthesizing them by means of a unified taxonomy that encompasses the aspects considered by other proposals, and it captures the overall characteristics of KPIs. Since most of the literature centers on the definition of KPIs, we mainly focus on such an aspect of KPIs management. Our work is intended to provide remarkable benefits such as enhancing the understanding of KPIs management, or helping users decide about the most suitable solution for their requirements.

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Clinical guidelines and protocols are used to aid decision making in health care. This paper presents a modelbased approach to the development of decision support systems for clinical guidelines. The guidelines are modelled using the UML Statechart language and the final system is automatically generated using an automated model transformation. Our approach is illustrated with a Spanish clinical guideline developed on the basis of a guideline published by the well-known National Guideline Clearing House (NGC).