DOI: http://dx.doi.org/10.31011/1519-339X.2018a18n85.13 Objetiva-se descrever o processo de cicatrização de pacientes com úlceras diabéticas tratadas com fator de crescimentoepidérmico recombinante humano (rhEGF), e a colonização por Staphylococcus aureus e Pseudomonas aeruginosa. Estudode casos de pacientes com úlceras diabéticas tratadas com rhEGF acompanhados ambulatorialmente em um hospitaluniversitário. A coleta de dados ocorreu entre abril e agosto de 2017, com a obtenção de características clínicas, incluindomensuração das áreas e registros fotográficos das lesões, bem como, coleta de material biológico por swab. A análise dedados foi feita por estatística descritiva. O cálculo da taxa apontou 100% de cicatrização no paciente 1 e 30% no paciente2. Em relação ao tecido presente no leito da ferida, nota-se um aumento do tecido de granulação e epitelização e umadiminuição do tecido de esfacelo. Quanto ao exsudato, houve uma redução na quantidade presente na ferida ao fim doestudo. Não foram observados sinais clínicos de infecção nas feridas, os resultados das análises microbiológicas indicaramque a colonização microbiana por S. aureus e P. aeruginosa manteve-se no paciente 1 e foi minimizada no paciente 2. Concluise que a aplicação do rhEGF foi favorável na cicatrização de úlceras diabéticas e no controle microbiológico.Palavras-chave: Pé Diabético; Fator de Crescimento Epidérmico; Staphylococcus Aureus; Pseudomonas Aeruginosa;Enfermagem. ABSTRACTThe aim is to describe the healing process of patients with diabetic ulcers treated with recombinant humanepidermal growth factor (rhEGF), and colonization by Staphylococcus aureus and Pseudomonas aeruginosa. Casestudy of patients with diabetic ulcers treated with rhEGF with outpatients in a university hospital. Data collectiontook place between April and August 2017, obtaining clinical characteristics, including measurement of areas andphotographic records of the lesions, as well as collection of biological material by swab. The data analysis was doneby descriptive statistics. The calculation of the rate indicated 100% healing in patient 1 and 30% in patient 2. Inrelation to the tissue present in the wound bed, there is an increase of granulation tissue and epithelization anda decrease of the shedding tissue. As for the exudate, there was reduction in the amount present in the wound atthe end of the study. No clinical signs of infection were observed in the wounds. The results of the microbiologicalanalyzes indicated that microbial colonization by S. aureus and P. aeruginosa was maintained in patient 1 and wasminimized in patient 2. It concluded that the application of rhEGF was favorable in cicatrization of diabetic ulcersand in microbiological control.Keywords: Diabetic Foot; Epidermal Growth Factor; Staphylococcus Aureus; Pseudomonas Aeruginosa; Nursing
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