This attempt at circuit level single event effects (SEE) hardening of SiGe HBT logic provides the first reported indication of the level of sensitivity in this important technology. Characterization over data rate up to 3 Gbps and over a broad range of heavy ion LET's provides important clues to upset mechanisms and implications for upset rate predictions. We augment ion test data with pulsed laser SEE testing to indicate the sensitive targets within the circuit and to provide insights into the upset mechanism(s).
A new imaging device, the dynamic spatial reconstructor (DSR), is described. It differs from commercially available computed tomography scanners in several ways. It images a volume rather than a slice; it images the volume in stop-action to minimize blurring due to motion; and it repeats the scan 60 times per second so that the functional movements of heart muscle and lung tissue and the distribution of roentgen contrast medium in blood can be quantitated in any portion of the body, especially in the heart, great vessels, and lungs. The system is under evaluation as a research tool for physiologic and, ultimately, clinical investigations.
Large changes in stroke volume and peripheral vascular resistance were induced by varying the heart rate and by intra-aortically infusing acetylcholine or angiotensin II in six dogs with heart block and electromagnetic flowmeters chronically implanted around their ascending aortas. Changes in stroke volume, aortic and atrial pressures, and systemic resistance were monitored continuously for 3-6 hours under morphine-pentobarbital anesthesia. The characteristics of diastolic pressure decay at heart rates ranging from 60 beats/min to 200 beats/min and during transient periods of asystole were studied, especially with reference to the distortions caused by reflected pressure waves. The diastolic phase of pressure pulses recorded over a segment of the thoracic aorta several centimeters long centered about 4 cm cephalad to the dorsal insertion of the diaphragm could be closely approximated by a straight line on a semilogarithmic scale. Under the conditions of these experiments, changes in the slope of that line and of its reciprocal, the time constant, correlated well with concomitant variations in peripheral vascular resistance. This relationship appears to be of practical value for continuous monitoring of systemic resistance directly from the diastolic segments of pressure pulses recorded from the lower thoracic aorta.
KEY WORDSatrial-ventricular pacing dog vasoactive drugs peripheral vascular resistance central aortic pressure decay • The contour of the arterial pressure pulse varies dramatically during its transmission down the arterial tree, and the pressure decay during diastole is generally not a monotonic function of time (1-4). However, a relatively smooth diastolic pressure decay has been described for aortic pressure pulses recorded near the dorsal insertion of the diaphragm (5, 6); this observation has been confirmed repeatedly in our laboratory. An initial objective of this study was to determine how uniformly an approximately monotonic diastolic decay of the aortic pressure pulse could be recorded from this particular site in the aorta in different dogs and during widely different hemodynamic conditions. Secondarily, a time-independent method of characterizing this pressure decay, presumably caused by drainage of blood from the large arteries to the periphery, was sought. If such a time-independent characterization could be established, it would allow extrapolation into the immediately preceding or subsequent systolic periods of the decrement in aortic pressure due to peripheral flow. If possible, this extrapolation would provide a means of "correcting" aortic pressures during systole for the drainage of blood from the great arteries during ventricular ejection. This increment in aortic pressure due to ventricular ejection might be directly related to individual values of stroke volume by, at worst, a small number of calibration factors or, at best, a single easily determined constant multiplier.When pressure pulses were recorded from the above-mentioned specific aortic location in preliminary experiment...
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