Diabetes melitus (DM) merupakan kelompok penyakit metabolik yang berkaitan dengan meningkatnya glukosa darah dan diperkirakan akan meningkat secara drastis dan terjadi ledakan yang luar biasa dalam 1 atau 2 dekade mendatang. Diabetes melitus yang paling sering terjadi saat ini adalah diabetes melitus tipe II. Hiperglikemik kronis pada diabetes melitus berkontribusi terhadap munculnya berbagai komplikasi berupa kerusakan, disfungsi dan kegagalan berbagai organ seperti mata, ginjal, saraf, jantung dan pembuluh darah. Penderita DM cenderung berisiko 17 kali lipat terjadi gagal ginjal kronik.
TujuanUntuk mengetahui hubungan antara diabetes melitus tipe II dengan kejadian gagal ginjal kronik di Rumah Sakit PKU Muhammadiyah Yogyakarta Periode 1 Januari 2011 -Oktober 2012.
MetodePenelitian ini merupakan penelitian deskriptif analitik dengan metode cross sectional. Data diambil dengan metode consecutive sampling dari data sekunder berupa catatan rekam medis pasien dengan diabetes melitus tipe II di Rumah Sakit PKU Muhammadiyah Yogyakarta periode Januari 2011 -Oktober 2012. Analisis data dilakukan dengan uji Chi-Square.
HasilTerdapat hubungan bermakna antara diabetes melitus tipe II dengan gagal ginjal kronik dengan nilai p = 0,000 (p < 0,05) dan Confidence interval (CI) 2,3-7,8.
ABSTRAK IMT (OR=0,60, 95% CI=0,79, p=0,001), riwayat mendengkur dalam keluarga (OR = 4,92, 95% CI=1,31, p=0,002) dan lama tidur <7 jam dalam 24 jam (OR=5,14, 95% CI=1,23, p=0,015
ABSTRACTBackground: Obstructive sleep apnea (OSA) is common condition in commercial drivers while overweight and obesity as the most important risk factors. This study aimed to know the clinical symptoms and risk factors of OSA in overweight and obese taxi drivers in Jakarta, Indonesia.
Background: Heart failure is a major health problem in the world. It is associated with high morbidity and high mortality especially in elderly patients. Most studies reported that N terminal pro-B type natriuretic peptide (NT-proBNP) is used in the diagnosis of heart failure, but tests in determining severity levels of heart failure in the elderly remains unclear.Objective: This study is to determine differences of NT-pro BNP levels based on severity of heart failure in elderly patients. Methods: This was an observational study with a cross sectional design. Its subjects were patients with heart failure and age of ≥ 60 years. Patients were divided into two groups: mild and severe heart failure groups according to severity of heart failure based on New York Heart Association (NYHA). The NT Pro-BNP levels were measured for all subjects in both groups. All obtained data was analysed by using unpaired t test and was considered significant if p <0.05. Results: This study involved 24 subjects. The mean age of the subjects was 64.50 ± 4.65 years with a minimum age of 60 years and a maximum age of 78 years. The NT pro-BNP levels in the severe heart failure group (1.2587.58 ± 574.85 pg/ml) was higher than the mild heart failure group (867.83 ± 333.27 pg/ml), andit was statistically significant with p = 0.040.
Conclusion:The levels of NT-pro BNP serum in the elderly patients with severe heart failure (NYHA III-IV) were significantly higher than in patients with mild heart failure (NYHA I-II).
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