The positive association between pulp necrosis and crown discoloration should be considered with caution once the diagnosis of pulp necrosis was performed by limited criteria.

Objective The aim of this systematic review and meta‐analysis was to determine the impact of dental pain on oral health‐related quality of life (OHRQoL) in children and adolescents. Methods Electronic and manual searches were performed with no restrictions of language or year of publication. The PECO strategy was used to identify observational studies involving participants up to 19 years of age with dental pain and to those without dental pain to determine the impact of this condition on OHRQoL. The methodological quality of the studies was appraised using the Fowkes and Fulton checklist. Meta‐analysis was conducted by subgroups, based on OHRQoL questionnaires and effect measures. The quality of evidence was evaluated using the GRADE approach. Results Sixteen studies were included in the systematic review and fourteen in the meta‐analysis. The methodological quality of four of these studies was considered poor. The pooled results of the subgroup analysis (SOHO‐5, B‐ECOHIS and Child‐OIDP) showed that children with dental pain had a 3.64‐fold greater chance of a negative impact on OHRQoL ([log] 95% CI: 2.80‐4.72; I20%; P < .001). The second meta‐analysis (Child‐OIDP, SOHO‐5 and CPQ8‐10) demonstrated statistical significance (SMD 0.79; 95% CI: 0.43‐1.16; I292%; P < .001), as did the pooled results considering the B‐ECOHIS ([log] OR 7.75; 95% CI: 4.59‐13.11; I284%; P < .001). The certainty of evidence in all meta‐analyses was low. Conclusions Although the quality of the evidence is low, dental pain has a negative impact on OHRQoL.

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Background/Aim Dr. Jens Ove Andreasen, the “father” of dental traumatology, passed away on September 26, 2020. As a tribute, the aim of this study was to catalog and analyze the top 100 most‐cited papers (co)authored by Dr. Andreasen. Materials and Methods A bibliometric analysis was conducted on October 21, 2020, in the Web of Science Core Collection (WoS‐CC) database. The numbers of citations in the WoS “All Databases” section, Scopus, and Google Scholar databases were cross‐matched. Two researchers collected the following bibliometric data: title, number of citations, authors, country, year, journals, study design, and theme. The VOSviewer software was used to generate collaborative network maps for the authors and keywords. Results Of 194 papers identified in WoS‐CC, a list was compiled with the 100 most‐cited papers (co)authored by Dr. Andreasen. The number of citations of each paper ranged from 24 to 365 (mean: 85.4). Nine papers were cited more than 200 times. Most papers were published in Dental Traumatology (55%), between the 1990's and 2000's (60%), with a laboratory design (40%). One hundred and nine (co)authors, from 19 countries were identified in the top 100 most‐cited papers. Dental traumatology was the most studied theme (52%). Conclusions The top 100 most‐cited papers (co)authored by Dr. Jens Ove Andreasen were composed mainly of laboratory and observational studies, published mostly in Dental Traumatology. The present study was a humble homage to highlight the importance of his research and work. However, his legacy goes beyond the numbers and will always remain unsurpassed.

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Objective: There is a lack of high-quality evidence on the efficacy of the non-instrumentation endodontic treatment (NIET) in primary molars, compared to the conventional endodontic treatment technique. This protocol describes a multicenter randomized clinical trial that aims to evaluate the efficacy of a NIET technique for primary molars using a paste containing antibiotics (chloramphenicol and tetracycline – CTZ group) compared to a control group of conventional technique and root filling with zinc oxide eugenol (ZOE). Methodology: Children aged 3 to 9 years (N=218) will be randomly allocated to one of the groups: CTZ or ZOE. In CTZ, after the location of root canals entrance, irrigation will be performed using 1% sodium hypochlorite and CTZ paste will be placed over the root canal entrances, with no instrumentation of the root canals. In ZOE group, manual instrumentation of root canals with endodontic K-files will be performed, and then, the root canals will be filled with ZOE paste. At the same appointment, teeth will be restored with a double-seal of glass ionomer and a bulk fill resin composite. Children will be followed-up for 6, 12, 18 and 24 months. The primary endpoint will be the success of endodontic treatments evaluated by clinical and radiographic criteria after 24 months. Conclusions: NIET with CTZ paste could be an option to manage primary teeth, once the technique could have non-inferior efficacy to the conventional technique that involves root canal instrumentation. The approach could have good acceptance from children and parents considering the reduced clinical time.

Este estudo teve como objetivo traçar um panorama da produção científica internacional sobre a hipomineralização molar-incisivo e analisar os 100 artigos mais citados. Foi construída uma estratégia de busca para recuperar os estudos científicos sobre hipomineralização molar-incisivo na base de dados Web of Science até julho de 2020. Também foram identificados os 100 artigos mais citados sobre hipomineralização molar-incisivo. Dois pesquisadores realizaram a seleção dos artigos e extração dos dados. Gráficos bibliométricos foram criados no VOSviewer. Um total de 292 estudos sobre hipomineralização molar-incisivo foram incluídos. Austrália (51,0%) e Brasil (47,0%) foram os países com mais artigos publicados. A Universidade de Melbourne teve o maior número de publicações (18,5%). Os 100 artigos mais citados sobre hipomineralização molar-incisivo receberam uma média de 32,01 citações. A maioria dos artigos foi publicada entre 2013 e 2016 (52,0%). O tópico mais frequente foi a prevalência da hipomineralização molar-incisivo (30,0%), o desenho de estudo mais frequente foi o transversal (45%). Não foram encontradas correlações significativas entre o Fator de Impacto do periódico (2019) o total de citações no WoS (p=0,076) e Google Acadêmico (p=0,411). Este estudo bibliométrico identificou as tendências globais sobre a atividade de pesquisa sobre hipomineralização molar-incisivo.