Patients with end-stage renal disease (ESRD) are at increased risk of haemostasis disorders which result from changes in plasma and platelet (PLT) components [1]. Haemodialysis (HD) is the most common method of treatment used in patients with ESRD [2]. The contact between blood and the artificial surfaces of dialysis machines increases PLT reactivity and the production of coagulation factors. Consequently, this may lead to the occurrence of coagulopathy. It may also affect the natural process of blood clot dissolution (fibrinolysis) [3]. Concomitantly, damage in the vascular endothelium and changes in the activity of proteins participating in the coagulation cascade during the course of the ESRD may pose a risk of haemorrhage [1]. Furthermore, HD may only replace about 10% of proper
Anaesthesiologists strive to make the perioperative period as safe as possible. Platelet function assessment should be considered in every patient in whom haemostatic disturbances are suspected. MEA provides support for clinical decision-making, especially in patients who undergo haemodialysis or require antiplatelet therapy, and are in need of emergency surgery.
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