A modified hen's egg chorioallantoic membrane (HET-CAM) test has been developed, combining ImageJ analysis with Adobe(®) Photoshop(®). The irritation potential of an ophthalmic medicine can be quantified using this method, by monitoring damage to blood vessels. The evaluation of cysteamine containing hyaluronate gel is reported. The results demonstrated that the novel gel formulation is non-irritant to the ocular tissues, in line with saline solution (negative control). In conclusion, the modification of the established HET-CAM test can quantify the damage to minute blood vessels. These results offer the possibility to formulate cysteamine in an ocular applicable gel formulation.
Two studies are reported which assess the proclivity of itidividuals to increase the integrative cotnplexity of social, tnoral, or religious thinking when protnpted to do so. We also examined the influence on complexity of topic area and respotidetits' religiosity. Iti both studies significant increases iti complexity were obtained when participants were prompted to differentiate and integrate material, suggesting that an important distinction needs to be made between competence and performance with respect to complexity. However, there was some evidence that prompting complexity was more effective in eliciting differentiation than integration. Both studies indicated that overall, religious orientation was not a significant predictor of integrative complexity, nor did it interact with other factors (including religious vs. nonreligious content of stimulus materials). Finally, there was some evidence that complexity may vary across diiferent content areas, and this variation may be differentially affected by prompting for complexity.Fundamental to social cognitive analyses of human behavior is the assumption that the social perceiver engages in an active process of sim-
The aim of this study was to investigate the relationship between pointing production in infants and two types of event perception factors: spatial localization (e.g. eccentricity of visual events with respect to an initial fixation point) and salience of targets (addition to visual events of sound or object translation through space). Three experiments revealed that target characteristics, such as internal movement, sound, vanishing and translation through space (including disappearance) significantly influenced the incidence and latency of pointing, whereas the main effect of target localization was to determine which hand does the gesture. In particular, there was an advantage to the right side of the visual field in eliciting pointing when there is competition between targets. Finally, for events involving auditory‐visual stimulation females made more right‐handed points than males. The general advantage of the right hand for pointing may offer further evidence for a specific link between pointing, cerebral dominance and the transition to speech.
While most studies using the task of reading spatially transformed text do not reveal evidence of specific perceptual transfer, a study by Masson (1986, Experiment 3) provides clear evidence of such effects. Several experiments were designed to identify the basis for this empirical discrepancy. The only substantive evidence of specific perceptual transfer occurred when the words were presented in an unfamiliar typography, although each study suggested a trend toward perceptual specificity effects. The results are discussed in terms of Graf and Ryan's (1990) ideas about the role of distinctive memory representations.
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