Aim To describe the clinical characteristics and therapeutic options available to paediatric patients with cluster headache. Method Based on a literature search of the medical databases PubMed, LILACS, and Web of Science and using selected descriptors, we carried out a systematic review of case reports on cluster headache in paediatric patients published from 1990 to 2020. Results Fifty‐one patients (29 males, 22 females) with a mean (SD) age of 9 years 7 months (3y 10mo; range 2–16y) were diagnosed with cluster headache. The mean (SD) diagnosis was made 27.8 months (26.2mo) after the onset of cluster headache. Pain occurred at night or on waking up (76.5%) and consisted of 1 to 3 attacks per day (62.7%) lasting 30 to 120 minutes (68.6%). Headaches were unilateral (90.2%), had a pulsatile character (64.7%), and severe intensity (100%). There were autonomic manifestations (90.2%) predominantly ipsilateral to pain, in this order: lacrimation; conjunctival injection; nasal congestion; ptosis; eyelid oedema; and rhinorrhoea. Sumatriptan and oxygen inhalation were the most effective treatments for acute manifestation. Prophylaxis, corticosteroids, verapamil, and gabapentin were the most effective drugs. Interpretation Due to the small number of published studies, this review could not provide reliable data; however, it appears that cluster headache in children and adolescents is similar to adults, both in clinical characteristics and treatment. Cluster headache in children and adolescents is poorly studied. Cluster headache is uncommon before 10 years of age and diagnosis is difficult in the first few years of life. Treatment of cluster headache in children and adolescents is similar to that used in adults. The notion of the effectiveness of prophylactic treatment is based only on authors’ experience.

Objective To analyze the clinical and obstetric aspects of pregnant women with COVID-19. Methods A systematic literature review in the MEDLINE/PubMed, LILACS, SCIELO, and CNKI databases was performed from March to May 2020, with the descriptors: Pregnancy; 2019-nCov; Coronavirus; SARS-Cov-2, Covid-19. Of those chosen were original titles, without language and period restriction and that addressed pregnant women with a clinical and/or laboratory diagnosis of COVID-19. Revisions, editorials, and duplicate titles were excluded. The Newcastle-Ottawa (NOS) and Murad et al. scales were used to assess the quality of the studies. Results We included 34 articles with 412 pregnant women infected with severe acute respiratory syndrome (SARS-Cov-2), with an average age of 27.5 years of age and 36.0 gestational weeks. The most common symptom was fever (205 [49.7%]), and 89 (21.6%) pregnant women progressed to severe viral pneumonia. Laboratory tests showed an increase in C-reactive protein (154 [37.8%]), and radiological tests showed pneumonia with peripheral ground-glass pattern (172 [51.4%]). Emergency cesarean delivery was indicated for most pregnant women, and the most common gestational complication was premature rupture of ovarian membranes (14 [3.4%;]). We detected 2 (0.5%) neonatal deaths, 2 (0.5%) stillbirths, and 1 (0.2%) maternal death. Conclusion Pregnant women with COVID-19 presented a clinical picture similar to that of non-infected pregnant women, with few obstetric or neonatal repercussions. There was a greater indication of cesarean deliveries before the disease aggravated, and there was no evidence of vertical transmission of the infection.

Introdução: o acompanhamento pré-natal é essencial para a identificação de possíveis riscos na gestação, estando relacionado à diminuição da morbimortalidade materno-fetal. Durante a pandemia da Covid-19, foram grandes os desafios para a efetividade deste serviço, sendo criadas então diversas estratégias para o aumento da adesão à assistência pré-parto, tendo a telemedicina se destacado nesse cenário. Objetivo: Analisar as medidas adotadas para a manutenção da assistência pré-natal em meio à pandemia da Covid-19. Métodos: Revisão integrativa da literatura, realizado nas bases de dados médicos PubMed, LILACS e Scielo em julho de 2022. Resultados: Foram selecionados 30 artigos com base nos critérios de inclusão e exclusão. Discussão: Com a pandemia da Covid-19 várias estratégias para adesão à assistência pré-parto tiveram que ser criadas, como plataformas de comunicação online, aplicativos, formulação de materiais para serem postados com assuntos propostos por pacientes e pessoas da comunidade. Porém, os métodos digitais para aconselhamento não foram os únicos utilizados, teve-se também consultas presenciais para acompanhamento da gestação, mas com o número reduzido, nas quais eram utilizados todos os equipamentos necessários para um adequado distanciamento social. Conclusão: A pandemia da Covid-19 representou um período de limitações e adequações para que a assistência ao pré-natal se mantivesse adequada. Para isso, os diversos países criaram dispositivos para garantir esse acesso às gestantes, sendo o principal deles, a telessaúde, a qual, apesar de suas diversas restrições, trouxe diversos benefícios para o acompanhamento adequado do pré-natal.

OBJETIVO Descrever as caracter ısticas cl ınicas e as melhores opc ßões terapêuticas para cefaleia em salvas na idade pedi atrica.M ETODO Com base em pesquisa bibliogr afica nas bases de dados m edicos PubMed, LiLacs e WoS e usando descritores selecionados, analisamos todos os relatos de casos de cefaleia em salvas em idade pedi atrica publicados de 1990 a 2020.RESULTADOS Cinquenta e um pacientes (29 meninos e 22 meninas) com idade m edia (DP) de 9 anos e 7 meses (3 anos e 10 meses), variando de 2 a 16 anos, foram diagnosticados com cefaleia em salvas. O diagn ostico m edio (DP) foi feito 27,8 meses (26,2 meses) ap os o in ıcio da cefaleia em salvas. A dor ocorreu a noite ou ao despertar (76,5%), uma a três crises por dia (62,7%), com durac ßão de 30-120 minutos (68,6%), localizada unilateralmente (90,2%), de car ater puls atil (64,7%) e intensidade severa (100%). Houve manifestac ßões autonômicas (90,2%), predominantemente ipsilaterais a dor, nesta ordem: lacrimejamento, injec ßão conjuntival, congestão nasal, ptose, edema palpebral e rinorreia. Sumatriptano e inalac ßão de oxigênio foram os tratamentos agudos mais eficazes. Na profilaxia, corticosteroides, verapamil e gabapentina foram os medicamentos mais eficazes.

IntroductionThe disease caused by the new coronavirus was named by the acronym COVID-19 which means “COrona VIrus Disease”, while “19” refers to the year 2019, when the first cases in Wuhan, China, were identified.ObjectiveOur objective was to identify the prevalence of headache and to know its clinical characteristics in COVID-19 patients, available in the literature.MethodsBased on a literature search in the major medical databases and using the descriptors “headache and coronavirus”, “headache and 2019-nCoV”, “headache and SARS-CoV-2”, “headache and coronavirus and 2019-nCoV” and “headache and coronavirus and SARS-CoV-2” we include articles published between January 2019 and April 2020. We found 94 articles, but only 13 met the inclusion criteria.ResultsIn 13 articles analyzed in this review, a total of 3,105 Chinese patients (51.6% men and 48.4% women) had laboratory diagnoses of COVID-19. In 240 (7.7%) patients, headache was an associated symptom of COVID-19, but in only 52 (21.7%) of them there was some information about the characteristics of this headache.ConclusionsCOVID-19 patients have several clinical manifestations, including headache that is nonspecific with a prevalence of 7.7%.