Extranodal lymphomas which present in the nasal cavity and/or the paranasal sinuses are rare. Thirty-eight patients with disease that was clinically limited to the head and neck (Ann Arbor Stages IE-IIE) were admitted between 1947 and 1983. Twenty-eight patients were treated with radiotherapy alone and 10 received combination chemotherapy in addition. The overall 5-year survival figure was 56%. The corresponding result for Stage IE was 67%. No patient with Stage IIE disease survived 5 years. Extent of the extranodal disease also influenced results for Stage IE patients who were treated with radiotherapy only. When the extranodal disease was staged using the American Joint Committee TNM system, the 5-year disease-free survival for T1 and T2 patients was 78% as compared with 19% for patients with T3 and T4 disease. The addition of combination chemotherapy improved results for patients with T3 and T4 lesions. Cancer 56:814-819, 1985. YMPHOMAS originating in the nasal cavity and/or L the paranasal sinuses are very uncommon. Gall and Mallory' reported only 2 cases from a series of 6 18 malignant lymphomas (0.3%) and Freeman et al.' cited 33 cases in a series of 1467 non-Hodglun's lymphomas (2%). Wong er al.' in a previous study of 128 patients with extranodal lymphomas of the head and neck found 16 (1 3%) cases. The incidence of lymphoma in relation to other malignant tumors of the nasal cavity and associated sinuses is also low representing less than Also, lymphomas presenting in this region are almost exclusively non-Hodgkin's lymphomas. The diffuse large cell variety is by far the most common.
The hepatic sonograms of 443 patients with lymphoma were reviewed. Of these patients, 357 had nonHodgkin lymphoma, while 86 had Hodgkin disease. Sonography was able to detect disease in 5.2% of the total patient population. Disease was found in 5.8% of Hodgkin patients and 5.0% of nonHodgkin patients. The various sonographic patterns of disease are described. Hypoechoic and diffuse disease were seen in both types of lymphoma, while target and echogenic lesions were only seen in nonHodgkin lymphoma.
Percutaneous aspiration biopsies of opacified retroperitoneal lymph nodes, and retroperitoneal, intraperitoneal and paraspinal masses were successfully accomplished in 14 of 17 patients. A 23-guage needle was utilized for the procedure which is performed under fluoroscopic guidance. Metastatic carcinoma, sarcoma and melanoma were readily identified by aspiration biopsy while the diagnosis of lymphoma, especially as to type, was more difficult. No significant complications have resulted from the passage of the needle through the peritoneal cavity.
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