Lymphomas of the head and neck: CT findings at initial presentation

Lee, Y Y; Tassel, Pamela Van; Nauert, C; North, Luceil B.; Jing, Bao-Shan

doi:10.2214/ajr.149.3.575

Cited by 53 publications

(23 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The CT findings of head and neck lymphomas described in previous literature also include an isodense mass with distinct margins, extranodal extension with less well-defined margins and areas of necrosis within the tumour matrix. 4,[23][24][25][26] To our knowledge, there are few reports that independently depict MR findings of non-MALT lymphoma in the parotid gland. The general description of MRI of head and neck lymphomas includes low signal intensity on T 1 weighted images and low to high signal intensity on T 2 weighted images, with variable, but usually low, enhancement following the introduction of gadolinium contrast material.…”

Section: Discussionmentioning

confidence: 99%

Non-Hodgkin lymphoma involving the parotid gland: CT and MR imaging findings

Zhu¹,

Wang²,

Yang³

et al. 2013

Dentomaxillofacial Radiology

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Non-Hodgkin lymphoma involving the parotid gland: CT and MR imaging findings

Zhu¹,

Wang²,

Yang³

et al. 2013

Dentomaxillofacial Radiology

View full text Add to dashboard Cite

show abstract

“…Lymphoma is the second most common primary malignancy occurring in the head and neck behind squamous cell carcinoma, while NHL accounts for 65-90% of all lymphomas occurring in the head and neck [1,2] .20-30% of NHLs are derived from extra-nodal sites [3] .Nonetheless, NHL with a primary site in the oral cavity is rare, and in the tongue base, even rarer [4,5].…”

Section: Introductionmentioning

confidence: 99%

Primary non-Hodgkin lymphoma of the tongue base: the clinicopathology of seven cases and evaluation of HPV and EBV status

Ren

Cheng

et al. 2020

Diagn Pathol

View full text Add to dashboard Cite

Objectives: Non-Hodgkin's lymphoma (NHL) primarily derived from the base of the tongue, is rare. Human papillomavirus (HPV) and Epstein-Barr virus (EBV) are important aetiological risk factors for tumours of the head and neck. This study describes the clinicopathological features of NHL in the tongue base and the status of HPV and EBV in these cases. Methods: Seven cases were identified from the Pathological Registry Database at Peking Union Medical College Hospital (PUMCH). The study utilized immunochemistry, in situ hybridization (ISH), and gene rearrangement to confirm the disease and and performed a clinical follow up for each case. Results: All 7 lymphomas were localized at the base of the tongue. Six of the cases exhibited tongue base masses with smooth surface membranes. One case presented as multiple deep ulcers. The most common histologic subtype was diffuse large B-cell lymphoma (DLBCL), which occurred in five cases. The other two cases were mantle cell lymphoma (MCL) and peripheral T cell lymphoma, not otherwise specified (PTCL, NOS). One of the DLBCL cases was positive for HPV DNA and diffusely expressed P16 protein. During the follow up period, the MCL patient and an elderly DLBCL patient died. The remaining five patients were alive through the end of follow up. Conclusions: Most lymphomas of the tongue base manifest as an endogenous mass without membranous change. The most common subtype of NHLs of the tongue base is DLBCL, and the occurrence at this site may have a good prognosis. With proper therapy, even late stage tongue base lymphomas can be suppressed and remain in remission.

show abstract

“…Hodgkin's disease accounts for 25% of malignant lymphoma in Western countries but only 4.8% to 8.5% in Taiwan and the Orient (Lee et al 2005). Hodgkin's disease may present as a painless mass in approximately 70% of cases, with the most common site being found in the neck and 60% to 80% of cases having enlarged cervical and/or supraclavicular lymph nodes (Lee et al 1987). On the other hand, nonHodgkin's lymphoma often presents as a painless lump in the neck, axilla and/or groin (Harnsberger et al 1987).…”

Section: Introductionmentioning

confidence: 99%