Subacromial impingement syndrome (SIS) is a frequent cause of shoulder pain. Our purpose in this double-blinded, randomized, and controlled study was to demonstrate whether the pulsed electromagnetic field (PEMF) provides additional benefit when used with other conservative treatment modalities in acute phase rehabilitation program of SIS. Forty-six patients with unilateral shoulder pain who had been diagnosed as having SIS were included in this trial. The cases were randomly separated into two groups. All cases received a treatment program for 3 weeks consisting of Codman's pendulum exercises and subsequent cold pack gel application on shoulders with pain 5 times a day, restriction of daily activities that require the hands to be used over the head, and meloxicam tablet 15 mg daily. One group was given PEMF; the other group was given sham PEMF daily, 25 min per session, 5 days per week for 3 weeks. Shoulder pain during rest and activity and which causes disturbance of sleep was evaluated using a visual analogue scale, and total Constant score investigated shoulder function. Daily living activities were evaluated by shoulder disability questionnaire. Results were assessed before and after treatment. When compared with the baseline values, significant improvements in all these variables were observed at the end of the treatment in both groups (p<0.05). No significant difference between treatments was observed for any of these variables (p>0.05). There is no convincing evidence that electromagnetic therapy is of additional benefit in acute phase rehabilitation program of SIS.
Objective: Patients with fibromyalgia syndrome (FMS) have mild cognitive dysfunction. Higher serum uric acid (UA) levels in some diseases are reported to be associated with cognitive impairment. Mean platelet volume (MPV) is an indicator of platelet activation. Activated platelets may play a role in neuroinflammation and cognitive dysfunction. The purpose of this study was to compare cognitive functions of FMS patients and controls and investigate the relation of serum UA and MPV levels with cognitive functions. Method: Fifty-four patients with FMS and 33 healthy controls were enrolled,retrospectively. Evaluations were performed with Visual Analog Scale (VAS), Fibromyalgia Impact Questionnaire (FIQ), Beck Depression Inventory(BDI) and to asses phychological status and cognitive impairment Mini Mental State Examination(MMSE) was used in both groups. Results: Mean VAS and sleep quality of FMS group were significantly higher than the control group (p<0.05). Mean MMSE score was statistically significantly lower in the FMS group (p=0.0001). There was not statistically significant correlation between serum UA levels and VAS pain/sleep quality, FIQ, BDI and MMSE scores (p>0.05). No significant correlation was found between serum MPV levels and VAS pain/ sleep quality, FIQ, BDI and MMSE scores (p>0.05) but declined cognitive functions were determined in the FMS group when compared with the control group. Conclusion: Declined cognitive functions were determined in the FMS the FMS group when compared with the control group. Although we did not determine an association of serum uric acid and MPV levels with cognitive functions, larger prospective studies with longer follow up periods are warranted to elucidate the role of these biomarkers in FMS and to determine the factors affecting cognitive functions.
ÖZETMetoklopramid, hiperemezis gravidarumda sık kullanılan dopamin reseptör antagonisti olan anti-emetik bir ilaçtır. Akut distoni, metoklopramid tedavisinin 1-3. günlerinde, özellikle çocuklarda ve genç erişkinlerde ortaya çıkan nadir bir yan etkidir. Bu makalede hiperemezis gravidarum nedeniyle metoklopramid kullanan ve buna bağlı distoni gelişen bir olgu sunulmuş olup hiperemezis gravidarum olgularında distoni gelişmesi durumunda bu tablonun metoklopramidin yan etkisi olabileceği hatırlanmalıdır. Anahtar kelimeler: Distoni, Metoklopramid, Hiperemezis Gravidarum Dystonia Caused by Metoclopramide Use in Hyperemesis Gravidarum: A Case Report ABSTRACT Metoclopramide is an anti-emetic drug used frequently in hyperemesis gravidarum with dopamine receptor antagonistic properties. Acute dystonia is a rare side effect of metoclopramide encountered especially in children and young adults at first 3 days of treatment. In this case report, dystonia developed after metoclopramide treatment in a woman with hyperemesis gravidarum is presented and it is emphasized that in women with hyperemesis gravidarum, dystonia might be regarded as a side effect of metoclopramide.
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