These results provide the first evidence that more than one angiogenic factor could be implicated in aberrant endometrial angiogenesis resulting in breakthrough bleeding in LNG-IUS acceptors.
Background: Self-medication is one of the components of self-care, which may treat the disease or result in worsening of the condition due to irrational use of drug.1 In developing countries like India, self-medication is a common practice as it provides a low-cost alternative for people who cannot afford the high cost of clinical service, and is time efficient.Methods: A total of 110 participants completed the study. A printed questionnaire was given to those who were willing to participate in the study and came to buy medicines without consulting a doctor to various pharmacy outlets.Results: Among the group of drugs used antibiotics were the common drugs used in rural area (74%) and cough suppressants (50%) in urban area. Symptoms for opting self-medication were fever and common cold in both the groups. Individuals in both areas took self-medication based on their previous prescriptions (rural 42% vs urban41.6%) and advertisements. Rural individuals preferred self-medication with the opinion of saving time and urban people felt that it was less expensive.Conclusions: There is a difference in the pattern self-medication among rural and urban individuals. It is also to be noted that use of antibiotics may result in problems related to drug resistance. So, it would be advisable to restrict the sale of antibiotics as over the counter drugs.
Adverse drug reaction (ADR) is defined as “any response to drug which is noxious or unintended and occurs at a dose normally used in man for prophylaxis, diagnosis or treatment of diseases or for modification of physiological function”. Among the ADRs reported, cutaneous drug reactions are most common. Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE), also known as baboon syndrome (BS), is included in the spectrum of systemically induced allergic contact dermatitis. Characteristics of SDRIFE include a sharply defined symmetric erythema in the gluteal area and in the flexural or intertriginous folds without any systemic symptoms or signs. We present a case of 30-year-old female with baboon syndrome after taking the combination of paracetamol and diclofenac. Awareness of SDRIFE (BS) as an unusual drug reaction is especially important since the connection between skin eruption and drug exposure may easily be overlooked or misdiagnosed.
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