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Background: Hypertensive disorders complicate 5-10% of all the pregnancies and preeclampsia is identified in 3.9%.Preeclampsia is a pregnancy specific syndrome characterized by the development of hypertension and proteinuria in the second trimester of the pregnancy. Microalbuminuria and elevated spot protein creatinine ratio are commonly found in preeclampsia. The aim of this study was to determine microalbuminuria and spot creatinine ratio in early pregnancy as predictors of pre-eclampsia.Methods: The study was conducted among 102 pregnant women by detecting the levels of albuminuria and spot protein creatinine ratio at 10-14 weeks period of gestation. Random urine sample of about 5 ml was taken to analyse the samples for microalbuminuria and spot protein creatinine ratio. All the women included in the study were followed up till delivery to rule out the possibility of developing preeclampsia depending on their microalbumin and spot protein creatinine ratio values.Results: Pregnant women who developed preeclampsia or eclampsia had significantly higher levels of microalbumin and spot protein creatinine ratio.Conclusions: A detailed study among a larger group of population is required to determine that microalbuminuria and spot protein creatinine ratio in early pregnancy are definitive predictors of preeclampsia.

Background: The aim of the study was to evaluate the ability of the random urine P/C ratio to predict significant proteinuria, as well as to introduce a diagnostic test for pre-eclampsia which will avoid the inconvenience and time consumption of 24-hour urine protein collection. The objective of this study was to compare spot urine protein- creatinine ratio with 24-hour urine protein for estimation of proteinuria in pre-eclampsia.Methods: A total of 50 pregnant women with pre-eclampsia were prospectively studied for proteinuria in Rajarajeswari medical college and Hospital Bangalore for a period of 9 months from September 2018 to May 2019. Spot urine specimens for measuring P/C ratio were obtained immediately before 24-hour urine collection. The correlation between the spot urine P/C ratio and urinary protein excretion in the 24-hour collections was examined using the Spearman correlation test.Results: PCR at a cut off value 0.15 g/mmol had sensitivity and specificity of 96.6% and 55% respectively. In prediction of proteinuria of 300 mg/24 hr positive predictive value and negative predictive value 76.3% and 91.6% respectively.Conclusions: We found that there was a strong correlation between 24-hour urine protein excretion and spot urine protein creatinine ratio in pre-eclamptic women. Spot PCR can be used as a reasonable alternative to 24-hour urine protein test which is a cumbersome.

Tubo-ovarian torsion is infrequent diagnosis, clinical picture is nonspecific and children cannot articulate their symptoms which make diagnosis as a challenge. High index of suspicious and early intervention prevents damage to adnexal tissue.