Signals designed for transmission over multiple transmit antennas are capable for achieving significant capacity gain. Traditional approaches aim at improving the single-user link with a centralized control over the set of transmit antennas. In this paper, by considering a set of independent and synchronized users communicating with the base station on the up-link, the joint signal can be viewed as space-time coded signal without a centralized control. Co-channel/inter-antenna interference presents a major impairment that limits the capacity. We propose a novel multiuser signal structure called interference-resistant modulation (IRM) to improve performance without coding nor bandwidth expansion. IRM can also be combined with fading-resistant modulation or space-time coding to yield additional gain when each user employs multiple transmit antennas. We prove that, both analytically and by simulations, the IRM with maximum-likelihood (ML) detection achieves the single-user performance asymptotically. Furthermore, to reduce the prohibitive complexity posed by ML detection, we propose a simple minimum-mean-square-error based precombining group detector and an interference cancellation scheme. It is shown that the proposed detector combined with IRM provides significant improvement over previous approaches.
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