Background: Dry eye disease and diabetic retinopathy are complications in diabetes mellitus. However association between diabetes mellitus type II and dry eye disease are still unclear. Objectives of this study objective is was to analyse association between dry eye disease and diabetic retinopathy in patients with type 2 diabetes mellitus. Materials and Methods: A prospective study on seventy patients of diabetis mellitus type II/patients undergone indirect ophthalmoscopy and retinal photography, and the dry eye syndrome analysis using tear break up time and Schirmer tests. Diabetic retinopathy was graded. Results: In this study, there was no association identified among the age, sex & duration of diabetes mellitus type II disease and diabetic retinopathy. 52.8% (n=37) patients were observed to be suffering from dry eye syndrome and it was common in older and female patients. Diabetic retniopathy observed in 67.1%(n=47) patients. Upon classification, 34.2% (n=24) belongs to non-proliferative diabetic retinopathy, 27.1% (n=19)belong to severe NPDR and 5.7% (n=4) belongs to proliferative DR. TBUP was observed as ≤10 seconds. Moderate NPDR was significantly high in diabetes mellitus type II patients with dry eye disease. Statistically significant association observed between diabetic retinopathy and dry eye disease. Conclusion:The dry eye disease prevalence observed as 52.8% patients. Statistically significant association observed between severity of dry eye disease with duration of diabetes mellitus disease and the degree of diabetic retinopathy. There was significant association identified between diabetic retinopathy and dry eye disease.
Background: Normal conjunctival flora have important role in the healthy functioning of eye like maintenance of surface homeostasis and prevention and/or causation of ocular infection. Objective of this study is to investigate the conjunctival aerobic bacterial flora in diabetic patients and nondiabetic subjects with regard to the management of diabetes which is assessed by glycated hemoglobin levels. Materials and Methods: A prospective study carried out to compare the conjunctiva microflora in 50 diabetes mellitus type II and age matched 50 non-diabetic healthy individuals. Swab was taken from all the participants by rubbing sterile cotton swab to inferior palpebral conjunctiva. Bacterial culture processed using blood agar, chocolate agar, eosin methylene-blue lactose sucrose agar and sabouraud dextrose agar. The bacterial flora identified using microbiology procedure. Results: The rate of bacterial isolate determined as 40% and 34% in diabetes mellitus type II and nondiabetic healthy subjects. In these diabetic group, 30% positive for Staphylococcus aureus, 20% for Escherichia coli, 10% for Klebsiella pneumonia, 10% for coagulase-negative Staphylococcus and 30% for more than one bacteria. In non-diabetic group, 52.9% positive for Staphylococcus aureus, 23.5% for coagulase-negative Staphylococcus (CNS), 5.8% for Klebsiella pneumoniae and 17.6% for more than one bacteria. There was no statistical significant difference observed in isolated bacteria in diabetic and nondiabetic groups. Gram negative bacterial colonization observed high in diabetic individuals (diabetic group, χ2= 0.156, p = 0.815 and in healthy non-diabetic group, χ2= 4.95, p = 0.035). Conclusion: Bacterial isolates were lower in diabetics younger than 40 years of age compared with older than 60 years of age. The conjunctival bacterial flora in diabetics differ from non-diabetic subjects. This should be considered preoperatively and postoperatively, for prophylactic and postoperative treatment should be administered accordingly to the diabetic patients.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.