Branched chain amino acids (BCAA) improve nitrogen balance and end-organ function in surgical patients, but are untested in marrow transplant recipients. We compared nitrogen balance, urinary 3-methylhistidine-to-creatinine ratio, upper arm anthropometry, serum prealbumin, and day to peripheral engraftment in a randomized, double-blinded trial between 45% (high-leucine) and 23% BCAA intravenous solutions in 40 adult leukemia patients for 1 month following allogeneic marrow transplantation. Nutritional support, provided at approximately 30 nonprotein calories/kg and 0.21 g nitrogen/kg ideal weight, did not differ between groups. Despite

In this manuscript we discuss a chemical kinetic model of blood coagulation by treatment with nonequilibrium atmospheric pressure dielectric barrier discharge. We then add kinetic data into a computational fluid dynamics model of blood flow treated by plasma and show that we are able to induce hemostasis. We then present initial experimental validation of these computational models using in vitro bovine blood samples.