Our study showed that the complications after laparoscopic surgery were lower than in open surgery. We recommend laparoscopic surgery for upper ureteral stones >1 cm because of lower postoperative complications, shorter hospital stay, and shorter time to convalescence, and better cosmetic results.
Background: Although there are a few studies on kinetic and kinematic parameters of scoliotic subjects, it is still controversial whether gait performance of scoliotic subjects differs from that of normal subjects or not. Moreover, there is lack of information regarding joint contact force of scoliotic on convex and concave sides. Therefore, this study examined these issues. Method: Two groups of children (healthy and children with scoliosis, each group consisting of 5 subjects) participated in this study. The force applied on leg and motions of body parts were evaluated using a Kistler force plate and motion analysis system, respectively. Joint contact forces, muscles length were evaluated in both groups and on both sides (in scoliotic subjects) with OpenSim software. The difference in the parameters between healthy children and scoliotic subjects, and also concave and convex sides, was determined using the independent [Formula: see text] test. [Formula: see text] value was set at [Formula: see text]. Results: The results of this study showed that there was no difference between the forces applied on the leg, range of motions of the joints (hip, knee, ankle, pelvic and trunk), muscles length and joint contact force, neither between normal and children with scoliosis, nor between concave and convex sides [Formula: see text]. Conclusion: The findings revealed that scoliosis deformity with curve less than [Formula: see text] does not have any significant effect on joint contact force, kinetic and kinematic parameters.
Background &Objectives:
Evaluation of estrogen receptor (ER), progesterone receptor (PR), and (human epidermal growth factor receptor-2) Her-2 on core needle biopsies (CNBs) is increasingly in use to diagnosis early breast cancer, but its concordance with surgical excision (SE) is not well documented.
Methods:
The study included 100 formalin fixed, paraffin-embedded specimens of invasive breast carcinoma archived in Pathology Department of Cancer Institute, Tehran, Iran, from 2011 to 2014. Immunohistochemistry was applied to detect ER, PR, and Her-2.
Results:
The current study findings indicated a significant correlation of 90% between CNB and SE specimens for
ER
expression. The correlation between CNB and SE specimens was estimated as 81% and 97.3% for PR and Her-2, respectively.
Discussion:
CNB can be performed confidently to determine ER and Her-2. For PR, results obtained from CNB should be considered
.
Background:
Sleep bruxism (SB) in children is commonly a self-limited problem; however, therapy of the condition may be needed to improve sleep quality of parents and children. Benzodiazepines have some success in controlling adult bruxism. The objective of this study was to evaluate the effect and the safety of a short course of diazepam on controlling SB in healthy children.
Materials and Methods:
In this double-blind, randomized placebo-controlled clinical trial, 109 children with SB were randomly assigned to three groups, receiving low or moderate dose of diazepam or placebo for 2 weeks. For children aged 2–8 years, the dose of 2.5 and 5 mg was considered as low and moderate dose consequently. In children >8 years, the doses were doubled. The severity of SB was evaluated at the beginning and also 2, 8, and 12 weeks thereafter. Data were collected by a questionnaire completed by parents including frequency of SB per week and per night and duration of each SB, as bruxism severity score (BSS). A mixed-model ANOVA was used to assess the differences of mean BSS between different groups and measurement times.
Results:
From 109 children recruited, 90 completed the study. After 2 weeks of intervention, the mean BSS decreased significantly in all groups (
P
= 0.0001), but it was not significantly different between groups in any of follow-ups (
P
= 0.554). Next-day sleepiness was assessed at week 2 of the study and was significantly higher in the groups using diazepam (
P
= 0.026).
Conclusion:
Short course of diazepam was not more effective than placebo for long-term control of SB in children.
Key Clinical MessageIn conclusion, we can focus on histologic features such as stellate reticulum, reverse polarization of basal cell layer nuclei, and luminal lamellated keratinization as distinguishing factors of ameloblastoma and SKCO. If there is any clinically doubt, molecular testing could be helpful.Abstract“Solid odontogenic keratocyst” is a rare variant of odontogenic keratocyst, which usually involves mandible. This case was presented as a unique variant of odontogenic keratocyst in an unusual site of left maxilla with extension to the maxillary sinus.
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