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PurposeNerve injuries formed during oral and maxillofacial surgical operations occur usually by crush or tension-type damages rather than incisions or ruptures. Such nerve injuries can be treated by providing regeneration with pharmacological agents without surgical intervention. The aim of this study was to determine and compare the effects of dexamethasone, B vitamin complex, and nerve growth factor on peripheral nerve regeneration with a local application on the inferior alveolar nerve. Methods Twenty-four Wistar Albino rats weighing 220-250 grams were used in the study. Experimental animals were divided into 4 groups. According to the groups, animals were treated with saline, dexamethasone, vitamin B complex and nerve growth factor. All animals were sacrificed on the 21st day and inferior alveolar nerves were resected for microscopic examination. Results The integrity and irregularities of myelin sheaths and vacuole formation were evaluated under a light microscope. Statistical analysis was performed with SPSS version 17.0. When histopathological findings were evaluated, it was observed that dexamethasone and vitamin B application triggered regeneration. However, regeneration in the group treated with nerve growth factor was much more obvious. Conclusions Local drug applications are beneficial for regeneration in inferior alveolar nerve injury. Considering their success, studies are needed to place growth factors in clinical practice.

This report aims to present 5 cases of intraoral lipoma with clinical findings, surgical treatment and histopathological features. Provisional diagnosis of minor salivary gland neoplasm, fibroma and lipoma was made for all of the cases according to clinical examination. Excisional biopsy was performed with blunt dissection. Lobular, yellowish, encapsulated masses were obtained from the patients and excised specimens were sent to pathology laboratory for histopathological analysis. After histopathological examination, all cases were diagnosed with simple lipoma. Successful healing of the oral mucosa was observed in postoperative period. The most important feature of these tumours is that they are asymptomatic. Differential diagnosis is important as it includes malign tumours and some genetic diseases that may be related to tumour.

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Faktör VIII veya IX eksikliğinde görülen hemofili, nadir görülen bir konjenital kanama bozukluğudur. Hemofili hastalarında diş hekimliğinde uygulanan invaziv tedaviler kanama riski oluşturur. Ayrıca oral hijyen eksikliğinde görülen dişeti iltihabı uzayan spontan kanamalara sebep olabilir. Bu hastalarda klinik yaklaşımdaki farklılıklara dikkat edilmeli ve hematolog konsültasyonu ile kanama kontrolü önlemleri alınmalıdır. Ayrıca oluşabilecek ağız hastalıklarını azaltmak için ağız hijyeni, diyet, koruyucu uygulamalar gibi unsurların üzerinde durulmalıdır.