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Objective: Comparing locked and unlocked uterine closure techniques in terms of bleeding control and uterine incision healing. Methods: The patients undergoing cesarean section in Sifa University Hospital between May - October 2012 were accepted to this prospective controlled study. Primarily, safety was evaluated. The hemoglobin count (HC) and serum creatine kinase (CK) levels of the patients in the locked (n = 47) and unlocked (n = 35) groups were measured just before and 24 hours after operation. Hemoglobin deficit, increase in CK and the additional hemostatic sutures were compared. Secondly, uterine scar healing was evaluated three months later. Scar thickness, niche and percentage of thinning of the scar region of the locked (n = 27) and unlocked (n = 32) groups were calculated and compared. Results: The hemoglobin deficit was similar in two groups. CK rise was less in the unlocked group but it was not significant (P = 0.082). Unlocked group needed more additional sutures (P = 0.016). The thickness of the niche and the percentage of thinning of the scar region were significantly less in the unlocked group (P= 0.002, P=0.000). Conclusions: Unlocked uterine closure technique is safe and has less damage to the myometrium.

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Patients treated with isotretinoin should be monitored with thyroid function tests.

Salivary cortisol and DHEA-S levels, as well as mood disorders, should be monitored in patients with HG, although further large, prospective studies are needed to confirm our results.

Vitamin D is a cholesterol derivative steroid hormone that, unlike other vitamins, can be synthesized in the human body. Apart from its known role in calcium metabolism, it has important additional roles in many cellular events by virtue of its autocrine and paracrine effects. It leads to anti-inflammatory and anti-infective responses and regulates cellular proliferation, differentiation, and insulin synthesis (1, 2). Recent studies have shown that vitamin D has an important role in both healthy pregnancy processes and long-term health of offspring. Recent evidence has suggested that vitamin D has an association with multifactorial diseases of pregnancy, such as bacterial vaginosis, preterm birth, gestational diabetes, and preeclampsia (3)(4)(5). In addition, some epidemiologic studies reported that there might be a relationship between allergic diseases, asthma, diabetes mellitus type 1, schizophrenia, and autism and maternal vitamin D deficiency (6-8).The prevalence of vitamin D deficiency in pregnancy is high all over the word. Classically, conditions, such as a low socioeconomic level, being of African or Latin American descent, obesity, dark skin color, wearing covering clothing, living in northern latitudes, and taking no vitamin D supplements, are known to be associated with vitamin D deficiency. However, high vitamin D deficiency rates have recently been detected in people not usually considered to be 'at risk': with a lighter skin color, have a holiday for a long time, have a higher socioeconomic level, living from sun-drenched, torrid zones, and those believed to have adequate sun exposure (9-11). The best indicator of vitamin D status is serum 25-hydroxyvitamin D3 (25(OH)D 3 ) concentration, because it reflects both dietary intake from vitamin D and cutaneous synthesis of vitamin D. However, there is no absolute consensus as to what a normal range for 25(OH)D 3 in pregnancy should be. Most authors agree that severe vitamin D deficiency should be defined by a 25(OH)D 3 concentration ≤10 ng/mL (≤25 Objective: The aim of this study was to determine the prevalence and the predictive factors of vitamin D deficiency in pregnancy and the compliance with "The National Vitamin D Support Program" at Turkey's easternmost and westernmost provinces. Material and Methods:Lifestyles of women at 24-28 weeks of pregnancy were assessed using a questionnaire form, and serum 25-hydroxyvitamin D3 (25(OH)D3) levels were measured.Results: Vitamin D deficiency (≤20 ng/mL) in pregnant women had a prevalence of 27.8% in İzmir and 76.3% in Erzurum. The compliance of "The National Vitamin D Support Program" was 8% in İzmir and 32.6% in Erzurum. Clothing style, fish consumption, seaside holiday duration, and 1200 IU/day vitamin D replacement had an effect on 25(OH)D 3 levels in pregnant subjects in İzmir, whereas only holiday duration and 1200 IU/day vitamin D replacement affected 25(OH)D 3 levels in Erzurum. However, when a threshold for 25(OH)D3 level was considered ≥32 ng/ mL, lifestyles did not affect 25(OH)D 3 level. Conclus...

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