Novel molecular iodine catalyzed cyclization reactions of 2-amino anilines with aryl alkyl ketones under oxidant and metal-free conditions are described. The reaction likely involves sequential C-N bond formation followed by C(CO)-C(alkyl) bond cleavage. Various 2-substituted benzimidazoles are obtained in moderate to good yields in a single step from readily available acetophenones, propiophenones, and phenylacetophenones.
Iodine-catalyzed, aerial oxygen supported C–C bond cleavage reaction of aryl alkyl ketones for the synthesis of benzoic acids and benzamides. Also benzylidene acetones and phenylacetylenes were converted to their aromatic acids at this conditions.
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