Background: Some studies reported the association between fibroids with uterine inflammation. By considering this hypothesis, the formation and recurrence of uterine fibroids can be prevented by diagnosis and treatment of inflammation, and complications and costs can be reduced. This study aimed to evaluate the association between chronic endometritis and uterine fibroids in non-menopausal women. Materials and Methods: This prospective case-control study was performed on non-menopausal women referred to Al-Zahra Hospital in Rasht during April 2019-April 2020. Non- menopausal women of reproductive age (20-55 years old) with abnormal uterine bleeding who were candidates for hysteroscopy based on medical history and ultrasound reports were included in this study. The case group with fibroids were divided into two groups of intramural and subserosal myoma group and submucosal group based on the location of fibroids. The control group was patients with abnormal uterine bleeding complaints and no uterine fibroid. Endometrial specimens were examined by a pathologist for histological and immunochemistry assessments. In interpreting the results of endometrial biopsy, a positive result was indicated by the presence of one or more plasma cells per 10 high power field. Data were gathered by a form including age, parity, history of recurrent miscarriage, patient’s complaint (abnormal uterine bleeding), hysteroscopic results (submucosal myoma-polyp-normal), uterine histology (polyp, endometritis, and hyperplasia) and prevalence of chronic endometritis based on plasma cell in the biopsy. Data were analyzed by SPSS software version 21. Data were reported by descriptive statistics including number, percent, mean and standard deviation. The normality of quantitative data was assessed by the Kolmogorov- Smirnov test. Mann-Whitney U test, Chi-square and Fisher exact tests were used to compare groups and logistic regression was used to control the effect of confounders. Results: The incidence of chronic endometritis was 39% (38 out of 97) and a higher incidence of chronic endometritis was noted in the case group than the control group (46% vs. 31%), No significant difference was observed between the two groups ( P > 0.05). However, the incidence of chronic endometritis in women with submucosal myoma was higher than the intramural and subserosal groups (64% vs. 37%) ( P = 0.04). To control the effect of age on the rate of chronic endometritis in both groups, no significant effect was observed in logistic regression. Conclusions: The results showed the overall incidence of chronic endometritis was higher than previous studies and also the incidence was higher and more significant in women with submucosal myoma than in the intramural and subserosal group. As in this study, authors assessed the association between chronic endometritis and uterine fibroids, further studies assessing...

Background Obtaining informed consent (IC) is essential for any diagnostic or therapeutic procedure. Objective IC is an important legal communication process between the patient and the physician. Methods In 2021, this cross-sectional study was performed in Alzahra Hospital. Eligible patients over the age of 18 years, who were candidates for elective gynecological surgeries under SA enrolled in the survey. A questionnaire containing demographic data and 20 specific questions divided into 4 areas (providing information, comprehensibility of the consent form, voluntary informed consent, and communication with the doctor), was completed via a direct interview. Results The data from 259 eligible patients were analyzed. In terms of providing information to the patient, comprehensibility of the consent form, and the voluntary obtaining consent were in poor condition. However, in terms of communication with the physician, 46.3% of the patients were in a good state and 20.1% were in an excellent state. A significant relationship was also observed between the level of education and the quality of obtaining IC (P=0.034). Conclusion It was concluded that the IC process was not acceptable in this academic center, and efforts should be made to improve the current conditions.

Background: Screening programs for the early diagnosis of breast cancer lead to perform several biopsies in order to determine the breast abnormalities found in sonography and mammography. According to gradually replacement of core needle biopsy instead of more invasive methods like open surgical biopsy, it seems necessary to study the concordance between biopsy results and non-invasive diagnostic methods in order to clarify ambiguous results and confirm the reliability of non-invasive methods. Objective: The objective of this study was to match the sonography and mammography reports with core needle biopsy in patients referred to Sahand core needle biopsy center. Materials and methods: This prospective cross-sectional study was performed on 240 patients referred to Sahand Center with sonography or mammography reports or by a surgeon for core needle biopsy. All the patients were examined by a gynecologist assistant and were asked about demographic information and their recent diseases. The matched sonography or mammography cases with pathology reports and positive predictive value based on comparison between them and pathology report were determined as standard diagnostic criteria. Then, data were statistically analyzed by SPSS v.21 software. Results: In this study, there was no statistically significant difference between sonography or mammography and pathology reports for categorizing patients in two distinct malignant and benign groups (p>0.05). There was also no difference observed in two age groups (p>0.05). In both sonography and mammography groups, the sensitivity and specificity were 60.32% and 92.96%, respectively. Moreover, the positive and negative predictive values of sonography and mammography were the same in both methods and were 70.37% and 86.56%, respectively. Conclusion: According to the significant concordance between sonographyand mammography with core needle biopsy, these non-invasive methods can be helpful in diagnosing malignant lesions and differentiating them from benign lesions; they are also affordable and available. The attention to underlying variables such as age, can improve sensitivity and specificity of non-invasive methods in comparison to invasive diagnostic methods.g.