Introduction: Tuberculosis (Tb) is one of the 10 causes of death worldwide. Indonesia ranks third in the world . This indicates that the behavior of prevention of transmission by Tb patients is not effective yet. The purpose of this study is to identify behavioral factors for preventing TB transmission based on the Health Promotion Model theory.Method: This research was conducted by using descriptive analytic design with cross sectional approach. Population of this research was 150 patient with Tb. Sample on this research was 108 respondents which were chosen by using simple size calculator technique. Independent variables in this research were behavior before sickness, cognizance of patient of Tb, perceived of benefits, perceived of barriers, self-efficacy, attitudes related to transmission prevention activitie and environmental influences. Dependent variable in this research prevention behavior of TB transmission. The data colleting technique used in this research was questionnaire which was analysed by Spearman’s rho test with <0,05 significance. Result: The result showed that preventive behavior of TB transmission was correlated with behavior before sick (r=0.239), cognizance of patient of TB (r=0.261), perceived of benefits (r=0.371), and family support (r=0.284). There was no correlation between perceived of barriers (r=-.113), self-efficacy (r=0,160), attitudes related to transmission prevention activities (r=-.097) and environmental influences (r=0.034). With preventive behavior of TB transmission.Conclusion:  Behavior of TB prevention is also influenced by behavioral factors before illness, knowledge of Tb, perception about the benefits of actions and family support. The Puskesmas was expected can improve Health Education by giving education about how to use mask well and shelter provision sputum in TB infection prevention behaviors in society.