The World Health Organization (WHO) defines traditional medicine as the sum total of the knowledge, skills, and practices based on the theories, beliefs and experiences indigenous to different cultures, whether explicable or not, used in the maintenance of health as well as in the prevention, diagnosis, improvement or treatment of physical and mental illness. Plants are traditionally used for treatment of bacterial infections. The aim of this study was to investigate chemical composition, nutritional evaluation and antibacterial activities of watermelon seeds. The qualitative phytochemical analysis of watermelon indicated that alkaloids were moderately present, tannins, saponins, flavonoids, and phenols were all present. The quantitative analysis of watermelon indicated 3.080 mg/g for alkaloids, 0.304mg/g for phenols, 0.117 mg/g for tannins, 0.200mg/g for saponins and 2.675 mg/g for flavonoids. The vitamin composition of watermelon seeds indicated 0.03 mg/100 g for vitaminB1, 0.01 vitaminB2, 0.64 mg/100g for vitaminB3, 0.24 mg /100 g vitaminB6 and 0.01 for vitaminB12.The bioactivities of extract were tested, against Proteus mirabilis, Bacillus cereus, Staphylococcus aureus, Escherichia coli, Necropsobacter rosorum, Tsukamurella hongkongensis, Lactobacillus sp, Staphylococcus petrasii, Neisseria sicca, Dietzi amaris, Pseudomonas oryzyhabitans, Klebsiella pneumoniae, Advenella incenata, Neiserria subflava and Serriatia marcescens. Researchers are advised to turn their attention towards plants products, which is most promising area in search of new biologically activity compounds with better activity against multi drug resistant strains and reduced antibiotic related side effects.
Traditional medicine also known as Indigenous or folk medicine comprises of knowledge systems that developed over generations within various societies before the era of modern medicine. The World Health Organization (WHO) defines traditional medicine as the sum of total of the knowledge, skills, and practices based on the theories, beliefs and experiences indigenous to different cultures, whether explicable or not, used in the maintenance of health as well as in the prevention, diagnosis, improvement or treatment of physical and mental illness. The column chromatography was used to collect the crude fractions; solvents like petroleum ether, chloroform and methanol were used. The antibacterial activities of the crude fractions of Calotropis procera (leaf and stem) were evaluated in this study using some selected microorganisms like Escherichia coli, Shigella dysenteriae ATCC 24162, Salmonella typhi and Klebsiella pneumoniae ATCC 34089, whereby the plant was extracted using (acetone, methanol and aqueous). The paper disc method was used after which the zone of inhibition around the discs was estimated. The results showed that in the leaf of the plant; E. coli with Aqueous-methanol fraction and K. pneumoniae ATCC 34089 with acetone-petroleum ether fraction had the highest yield of 30mm respectively while in stem; K. pneumoniae ATCC 34089 with methanol-methanol fraction had the highest yield of 25mm. The structural elucidation of the bioactive compounds in the extracts were evaluated using Gc-Ms (Gas Chromatography-Mass Spectophotometry) which reveals the chemical compounds like phenol, methyl palmitate, Phthalic acid, 9-octadecenoic acid and other compounds known for valuable antimicrobial, biological activities and antioxidant properties. The leaves and the stem are having good chemical compounds that can be responsible for the antimicrobial and antioxidant properties.Stevens [5].
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.