Type 2 diabetes mellitus (T2D) is a major cause of morbidity and mortality worldwide, associated to micro and macrovascular complications. A major risk factor for T2D is obesity. Gastrointestinal surgery was reported to facilitate glycemic control in type 2 diabetes (T2D) by reducing the needs for anti-diabetic medications. Non-obese T2D patients submitted to gastrointestinal surgery involving gastric resection and bypass of intestinal segments, arise as interesting model to dissect the gastro-intestinal (GI) mechanisms associated with diabetes improvement.
Introduction: Pure primary gastric squamous cell carcinoma is rare, accounting for 0.04-0.07% of all gastric cancers. The pathogenesis and behaviour are unclear and treatment strategy is controversial, and so, the prognosis is poor in almost all reported cases. The authors describe a rare case of long survival of the disease, and an unique case in an institution. Case Report: A Caucasian woman was referred to our hospital by a tertiary centre with a nonhealing, histologically inconclusive ulcer. Histologic examination of the biopsy taken during a repeated esophagogastroduodenoscopy revealed squamous cell carcinoma. The proposed treatment was total gastrectomy with D2 lymphadenectomy. Squamous cell tumor with no dysplasia or metaplasia was found in the specimen. Adjuvant chemotherapy was done with no relapse evident even 18 months
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