Primary pure squamous cell carcinoma of the stomach: Unique case in one institution

Abstract

Introduction: Pure primary gastric squamous cell carcinoma is rare, accounting for 0.04-0.07% of all gastric cancers. The pathogenesis and behaviour are unclear and treatment strategy is controversial, and so, the prognosis is poor in almost all reported cases. The authors describe a rare case of long survival of the disease, and an unique case in an institution. Case Report: A Caucasian woman was referred to our hospital by a tertiary centre with a nonhealing, histologically inconclusive ulcer. Histologic examination of the biopsy taken during a repeated esophagogastroduodenoscopy revealed squamous cell carcinoma. The proposed treatment was total gastrectomy with D2 lymphadenectomy. Squamous cell tumor with no dysplasia or metaplasia was found in the specimen. Adjuvant chemotherapy was done with no relapse evident even 18 months