Measles is one of the preventable infections that does not lose its relevance to this day. In Russia, as well as throughout the world, waves of an increase in the incidence of measles are still being recorded, so in 2019 the maximum incidence rate over the past 20 years (3.05 %ооо) was noted. According to the current Measles Elimination Program of the Russian Federation, each case of this infection is subject to investigation, based on the results of which the epidemiologist organizes measures to prevent its spread in the outbreak. The main anti-epidemic measures in this case are isolation of the patient (at home or in a hospital according to clinical indications) and vaccination of persons in contact with him who need it. Thus, in order to prevent the occurrence of secondary cases, it is necessary to determine the vaccination and infectious history of all persons in contact with the sick person and vaccinate them no later than the seventh day from the moment the outbreak was registered. To date, it is difficult to generalize data from investigations of measles cases, despite their value for epidemiological diagnosis and the development of epidemiological surveillance (ES) tactics. The aim of the work was to improve the information support for the investigation of measles cases by creating and analyzing a database. The authors proposed a method for summarizing and analyzing the results of the investigation of measles cases using the formation of a database. For this purpose, about 1000 acts and reports on the results of the investigation of measles foci (on paper) registered in Moscow in the period from 2013 to 2015 were analyzed. The data contained in these documents is entered into the database, systematized in separate blocks and processed by the appropriate software for the purpose of their subsequent accumulation, storage and analysis. Based on the results of the work, the age composition of measles patients was analyzed. It was found that children under 18 years of age were more likely to have this infection, while the largest share among them was in persons aged 3–6 (32.4 %) and 7–14 years (25.0 %). The use of the database made it possible to confirm the high epidemiological effectiveness of the measles vaccine — the protection factor (E) was 86 %. Using the database, it was found that adults aged 20–35 years old were most actively vaccinated in measles foci (vaccination coverage was 57.7 %). With the threat of this infection, only 25.9 % of children (under 17 years old) who needed vaccination agreed to be vaccinated, and the percentage of refusals varied from 69.8 % in the age group up to two years old to 42.3 % in the group 20–35 years old.
The article discusses the design of the Delta robot, which is part of a multirobotic system for aliquoting biological fluid. The purpose of the article is to obtain a dynamic model of the Delta manipulator using 3D modeling, which will allow studying the kinematic and dynamic characteristics of the manipulator for the specified parameters. A computer-aided design (CAD) system is used for modeling. The article presents an analytical calculation of the kinematic and dynamic parameters of the Delta manipulator in the RS structure, a solution to the inverse problem is presented. The process of creating a digital calculation model in the NX Nasrtan system is described. The preliminary calculation of kinematic and dynamic parameters made it possible to set parameters in the NX Nastran system to ensure the rotation of the drive shafts of the engines in accordance with the specified trajectory of the output link. For all parts of the manipulator, the center of mass is determined and the material is assigned. Motion simulation was carried out and dependences of changes in speeds, accelerations and movements of the manipulator links were obtained to implement the required trajectory of the mobile platform. This calculation allows you to build the trajectory of the output link with a given speed, setting the rotation of the drive links of the calculated model taking into account the forces of inertia.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.