Background: Malocclusion is caused by several factors such as sticking out the tongue, biting the lips, sucking the thumb and biting nails, and breathing through the mouth. This bad habit results in malocclusion which can reduce craniofacial development of orthodontic problems in children. One of the treatments for malocclusion in children with orthodontic problems is the use of myofunctional appliances. Myofunctional devices can properly restore orofacial muscles to normal anatomy. One way to overcome this bad habit is to use myobrace. Myobrace is a three-stage device system specifically designed to treat malocclusion and correct bad habits in children. Objective: To search the literature study on the effectiveness of miobrace in early correction of malocclusion development and in overcoming bad habits in children. Method: Data collection was carried out by searching literature on article search sites, namely Pubmed, Cochrane, Wiley, Google Scholar and Science Direct published from 2016 to 2021. The search was carried out from March to April 2021. Systematic exit using the keyword Malocclusion, Myobrace, Orofacial Myofunctional Therapy.
BACKGROUND: Periodontitis is a chronic inflammatory disease that causes damage to the supporting structures of the teeth, and if left untreated, it can lead to impaired function, appearance, pain, and tooth loss. Periodontitis is caused by bacteria that adhere to and grow on the tooth surface. The “red complex” bacteria consisted of Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia. These bacteria will trigger an inflammatory response in the body. Interleukin-6 (IL-6) is an IL that acts both as a pro-inflammatory cytokine, IL-6 is a stimulator for MMP production. To treat the periodontal disease can be through non-surgical therapy as well as surgical therapy, to maximize therapy, it is accompanied by antimicrobial therapy. However, because of the frequent use of antimicrobials, causing antimicrobial resistance in patients, the use of natural ingredients as additional therapy is very necessary for this study using Moringa leaves as a substitute for antimicrobials. AIM: This study aimed to determine the effectiveness of Moringa leaf in influencing the anti-inflammatory cytokine IL-6. The first benefit of this research is to provide scientific information in the field of dentistry regarding the effectiveness of Moringa leaves against red-complex bacteria P. gingivalis as a cause of chronic periodontitis through anti-inflammatory cytokine analysis. METHODS: The type of research that will be used is quasi-experimental with a post-test research design with a control group design. This study used a sample consisted of 30 Wistars (Rattus novergicus) and was divided into two groups based on periodontal tissue sampling as follows treatment group which was treated with extracts Moringa and control group with aquadest irrigation after bacterial induction in the gingival sulcus. Blood samples were taken on days 0, 1, 3, 5, and 7 and centrifuged obtain blood serum and serum cytokine levels (pg/mL) were quantified using a commercial ELISA IL-6 kit. RESULTS: This study obtained the results that there was a decrease in IL-6 in both groups on the 3rd day of observation (D3) where the treatment group given Moringa extract showed a greater decrease in IL-6 levels compared to the control group. There is a significant value in the comparison of IL-6 levels between the two groups with p-value: 0.000 (p < 0.05). CONCLUSION: Moringa oleifera leaf extract showed the anti-inflammatory effect on inflammation induced by the bacterium P. gingivalis. M. oleifera extract can reduce the production of the pro-inflammatory cytokine IL-6 induced by P. gingivalis bacteria in periodontitis.
Background: Class II malocclusion is a common condition. The most common clinical presentation is a mandibular deficiency. Treatment with functional devices is an option that can be used for the treatment of malocclusion. In an era of evolving treatments, Bionator is still widely used in clinical practice. Objective: The purpose of this systematic review was to analyze the effectiveness of the treatment of class II malocclusion with the Bionator device in the growth and development phase. Methods: Data collection was carried out by searching literature on article search sites, namely Pubmed, Cochrane, Wiley, Google Scholar and Science Direct which were published from 2011 to 2021. The search was carried out from March to April 2021. Data search was carried out systematically using the bionator keyword. malocclusion class II, orofacial muscles, growth and development. Results: After eliminating published articles, the title and abstract of each article in the analysis amounted to 132 articles, 106 articles were excluded. The full text articles from the exclusion results were re-analyzed and 16 articles were excluded. The text of the article is complete and meets the eligibility of as many as 10 articles. Conclusion: From all the studies reviewed, the Bionator device can improve class II malocclusion in children.
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