AbstrakPenyakit perlemakan hati non-alkoholik (non-alcoholic fatty liver disease) merupakan kondisi klinis yang sering ditemukan dalam bidang hepatologi. Salah satu faktor risiko penyakit ini adalah dislipidemia. Penelitian ini dilakukan untuk mengetahui distribusi frekuensi profil lipid pasien perlemakan hati non-alkoholik dengan dislipidemia.Penelitian dilakukan secara retrospektif di RS DR. M. Djamil Padang terhadap pasien perlemakan hati non-alkoholik dengan dislipidemia periode 2010-2013. Dari 118 pasien perlemakan hati non-alkoholik dengan dislipidemia hanya 43subyek yang memenuhi kriteria penelitian. Rata-rata umur subjek penelitian pada laki-laki adalah 48,53±11,92 tahun dan perempuan 49,58±11,01 tahun. Subjek penelitian didominasi oleh perempuan dengan perbandingan 1,5:1 terhadap laki-laki. Didapatkan pasien hiperkolesterolemia sebanyak 61,82% , hipo-HDL-emia 86,05%, hiper-LDL-emia 44,19%, hipertrigliseridemia 55,81%. Kesimpulannya, pada perlemakan hati non-alkoholik ditemukan kadar kolesterol total dan trigliserida yang tinggi, kadar LDL yang normal serta kadar HDL yang rendah. Kata kunci: Profil lipid, perlemakan hati non-alkoholik, dislipidemiaAbstract Non-alcoholic fatty liver disease is a clinical condition that is often found in the field of hepatology. One of the risk factors for this disease is dyslipidemia. This study was conducted to determine distribution and frequency of the lipid profile patients non-alcoholic fatty liver with dyslipidemia.A retrospective study was conducted at DR. M. Djamil Padang hospital to patients of non-alcoholic fatty liver with dyslipidemia within 2010-2013. A total of 118 non-alcoholic fatty liver with dyslipidemia patients only 43 subjects who met the study criteria.The average age of the subjects were males 48.53±11.92 years and women 49.58±11.01 years. Subject is dominated by women against men with 1.5:1 ratio. This study observed that patient with hypercholesterolemia as much as 61.82%, hypo-HDL-emia 86.05%, hyper-LDL-emia 44.19%, hypertriglyceridemia 55.81%.It can be concluded patient of non-alcoholic fatty liver disease with dyslipidemia has high total cholesterol and triglyceride levels, normal LDL levels and low HDL levels
AbstrakSirosis hati adalah stadium akhir dari penyakit hati kronik berupa proses fibrosis difus yang ditandai dengan perubahan arsitektur normal hati menjadi bentuk nodulus abnormal. Pada penderita sirosis hati ini sering terjadi penyakit infeksi akibat adanya imunosupresi. Hitung kadar limfosit total dapat digunakan untuk menentukan status imunitas penderita sirosis hati. Tujuan penelitian ini adalah mengetahui kadar limfosit total penderita sirosis hati. Jenis penelitian ini adalah deskriptif analitik. Populasi penelitian adalah penderita sebagai sirosis hati yang dirawat di Bagian Penyakit Dalam RSUP Dr. M. Djamil Padang pada tahun 2011. Sampel diambil dari populasi yang memenuhi kriteria inklusi dan eksklusi. Data diolah menggunakan uji Chi-square. Dari hasil penelitian didapatkan bahwa sebanyak 83,1% penderita sirosis hati memiliki kadar limfosit total yang rendah. Terdapat hubungan kadar limfosit total dengan berat ringannya penyakit sirosis hati dengan p<0,05. Sebanyak 49,2% infeksi ditemukan pada penderita sirosis hati. Kematian pada penderita sirosis hati akibat penyakit infeksi ditemukan 52,9%. Kata kunci: kadar limfosit total, sirosis hati AbstractLiver Cirrhosis is the end stage of chronic liver disease in the form of a diffuse fibrotic process characterized by changes in the normal architecture of the liver to abnormal nodules. In patients with liver cirrhosis is common infections due to immunosuppression. The total lymphocyte count can be used to determine the immune status of patients with liver cirrhosis. The purpose of this study was to determine total lymphocyte count of liver cirrhosis patients. This research design is descriptive analytic. The population is the liver cirrhosis patients as treated in the Internal Medicine Dr. M. Djamil Padang in 2011. Samples were taken from the population that meet the inclusion and exclusion criteria. The data processed by Chi-square test.The results of this study indicated that as many as 83,1% of cirrhosis patients have a low total lymphocyte count. There is a relationship of total lymphocyte levels with severity of liver cirrhosis with a value of p<0,05. The infections found 49.2% of cirrhosis patients. Mortality in cirrhosis patients due to infection was found 52,9%
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