We present a case of allergic reaction to buckwheat. Cases of occupational asthma and skin rashes have been reported in Spain after ingestion of this food, although to date, their number is very low [8]. Of note, thermal processing (toasting) of buckwheat would enable the patient's IgE to recognize a greater number of bands and thus increase its allergenicity. It is also important to highlight the role of buckwheat as a cause of allergic reactions because of its increasingly frequent use in cooking. Similarly, we must not forget that it is often a hidden allergen.
Transonic and EUROGINE ingredients: water, propylene glycol, carbomer, diazolidinyl urea, methyl and propyl parabens, and disodium ethylenediaminetetraacetic acid. How to cite this article: Martínez Ant on MD, J auregui I, Gal an C, et al. Two cases of allergic contact dermatitis to different elements in identical ultrasound gels. Contact
Background
Iodinated contrast media produce non‐immediate hypersensitivity reactions (NIHR). The goal of this prospective study was to determine the utility of skin tests and the subsequent tolerance to negative skin‐tested iodinated contrasts in patients with NIHR caused by iomeprol.
Methods
Prick and intradermal tests with iomeprol, iopamidol, iopromide, and iobitridol were performed in all patients. IV challenge with the causative contrast (iomeprol in 90%) was made if skin tests were negative. In case of a positive skin test with the causal contrast, or a positive challenge test with it, IV challenge test with an alternative, negative skin‐tested contrast was performed in all patients.
Results
Skin tests were positive in 47.6% (20/42) of patients with NIHR induced by iomeprol. Of the 66 challenge tests performed with negative skin‐tested iodinated contrasts, tolerance was confirmed in 35 (53%): 32 iomeron, 2 iobitridol, 1 iopamidol. Cross‐reactivity between iomeprol and iopamidol was 22% (4/20 in patients with positive skin tests and 5/21 in patients with negative skin tests).
Conclusions
Sensitivity of the skin tests was less than 50% NIHRs due to iomeprol, while the negative predictive value of skin tests in patients who tolerated challenges with alternative contrasts (mainly iopamidol) was 53% (35 tolerated out of 66 performed). The cross‐reactivity between iomeprol and iopamidol is high.
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