Abstract:The utility of The SF-36 questionnaire for evaluation of health related quality of life was not clear in elderly people. The Cross-Sectional study was designed and Iranian version of The SF-36 was administered to random sample of 100 old subjects over 60 years old. Finding showed good internal consistency over 0.7 for all subscales of questionnaire. Convergent validity was obtained for all subscales with comparison for General Health Questionnaire-28 (GHQ-28) but was not strongly at 2 subscales Role emotional and Role physical. Discriminant validity was addressed for gender but for age groups role emotional, mental health and general health subscales were not different significantly. A principal component analysis was leaded one factor structure. Evidence for reliability of the questionnaire was good. But validity appeared moderate satisfactory. However this questionnaire seems the only measure for assessment of health related quality at life among elderly population.

This study aimed to examine the association between smoking status and quality of life (QOL) in a population-based sample of Iranian adults. The study used data from the Isfahan Healthy Heart Program (IHHP). A total of 5830 participants were included. They were categorized as current, former, or never smokers. QOL was evaluated using the World Health Organization Quality of Life Questionnaire (WHOQOL-BREF), Persian version. Data entry was performed using SPSS (SPSS Inc, Chicago, IL) software version 13.0. QOL was associated with marital status (P = .014), education (P = .001), occupation (P = .007), and income (P < .000) among current smokers. After adjusting for sociodemographic characteristics, smoking decreased QOL among current (odds ratio [OR] = 0.98; 95% confidence interval [CI] = 0.97-0.99) and past (OR = 0.97; 95%CI = 0.95-0.98) smokers relative to never smokers. QOL is lower among Iranian current and past smokers, and the relation is independent of underlying sociodemographic factors.

This study aimed to investigate its effect on hematologic cancer patients. This was a randomized controlled trial assessing quality of life in patients with hematologic malignancies from a single institute in Hamedan. Patients were allocated into two study arms and in addition to their routine treatment received either daily naltrexone 3 mg capsules (treatment group) or 3 mg starch (placebo group) and were followed up for 5 months. Quality of life was measured using the EORTC QLQ-C30 in four points in time (at admission, 1, 3 and 5 months follow-up). Data were analyzed to compare quality of life in two groups. Totally, 89 patients were studied (45 in treatment group and 44 in placebo group). There were no significant differences between two groups either in demographic and clinical characteristics or in baseline quality of life scores. However, at 1 month, 3 and 5-month follow-up assessments significant differences were observed. In one month follow-up two groups were significantly different in social functioning (p<0.05) indicating a better condition in the treatment group. In the 3-month follow-up, social functioning, role functioning, nausea and vomiting and appetite loss were better in the treatment group (all p-values <0.05). In the 5-month follow-up, physical functioning, social functioning, role functioning, global quality of life, nausea and vomiting and appetite loss were significantly better in the nalterxone group. Low dose naltrexone is an effective drug in improving quality of life in patients with hematologic cancers.

Abstract:The purpose of this study was to determine the effect of "Zinc" & "Health Belief model" based education on viral upper respiratory tract infections in soldiers in Isfahan -2004Isfahan - -2005. It was a double -blinded randomized controlled trial, which was done among a group of soldiers by census. Soldiers were randomly divided into four groups. On the other hand four preventive measures were assumed regarding presence of education and zinc prescription, which were randomly allocated to four groups. Subsequently education was performed to change the health behavior of soldiers. Meanwhile tablets were distributed among all groups of soldiers. Data regarding incidence and duration of symptoms were gathered by different questionnaires filled by soldiers themselves and doctors and finally analyzed by SPSS 11.5 software through χ 2 , t-test and logistic regression. Common cold incidence in groups receiving zinc vs. placebo was significantly less. (P=0.001). Groups, which received education comparing to those, which didn't, were statistically the same 'regarding the incidence of common cold (P=0.37). Mean duration of symptoms was less in groups receiving zinc comparing to the groups, which received placebo as it was similar regarding education (P=0.007, 0.01). All of all 'this study showed that zinc consumption can decrease the incidence and duration of common cold. Education could promote some preventive behaviors and compliance to tablet consumption but had no effect on incidence. Decreased incidence by zinc consumption could be in part related to education through increased compliance for tablet consumption.