The main purpose of this study is to empirically test the moderating role of team climate between servant leadership, employee ambidexterity and work performance. Data were collected from 180 teachers working in different schools in Punjab, Pakistan. The sample was drawn using the convenience sampling technique. The direct and indirect hypotheses were tested using two-step Partial Least Square (PLS) path modelling. SEM has been used to analyze data. The findings of the research study designated the effect of servant leadership on work performance as essential. The results further revealed that in the relationship between servant leadership and work performance, team climate operates as a moderator, and this framework was mediated by employee ambidexterity. The work performance of teachers can be improved when the servant leaders encourage teachers to adopt ambidextrous activities by being exploration and exploitation according to the situation to meet challenges and overcome constraints. The study will act as a policy guide for Punjab School administration in areas such as employee performance enhancement through servant leadership style and employee ambidexterity, as well as team climate. The results of this study show that the impacts are tremendous and beneficial for the educational institutes of Pakistan.
In the present study efforts have been made to prepare sustained release matrix tablets of Lornoxicam. Matrix tablets were prepared by direct compression method by using Hydroxypropyl methyl cellulose K15 (HPMC- K15), Ethyl cellulose (EC) and Sodium carboxy methyl cellulose (Na-CMC) as polymers in different concentrations. A 3-factor 3- level Box-Behnken statistical design was used as an optimization tool having total of 17 experimental runs with 5 central points. All three polymers were selected as independent variables while %age drug release at various time intervals and hardness were used as dependant variables. In vivo studies were conducted on human plasma using Tenoxicam as internal standered. All the detections were made on SYKNM HPLC. Foriour Transform Infrared Spectroscopy (FTIR) and Differential Scanning Calorimetery (DSC) studies were conducted and no chemical interaction was found between drug and polymers. The drug release mechanism was mainly governed by non-fickian (anomalous) diffusion and zero-order (case II) transport diffusion. Regression analysis was performed on dissolution data obtained with the selected response variables and polynomial models were constructed. Polynomial models were further validated using one way ANOVA and results indicated that all the polymers used have significant effect on selected response (p>0.05). Contour plots and three dimensional response surface curves were drawn. In- vivo studies were conducted on two tablet formulation indicating slow and sustained release of the drug from matrix. From Behnken design it is possible to successfully formulate and optimize Lornoxicam sustained release matrix tablets with three polymers (HPMC- K15, EC and Na-CMC) in combination.
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