This study summarizes fetal anomalies that are diagnosed for the first time on routine ultrasound examination at 35-37 weeks' gestation. What are the clinical implications of this work?Ultrasound examination at 35-37 weeks' gestation may reveal new fetal abnormalities that could not be diagnosed at earlier examinations.

The glucose and protein content of the gingival fluid and blood of 10 diabetic patients and 10 control subjects with gingival and plaque indices of 1–2 were compared. Both the control and diabetic groups had similar blood and gingival fluid protein levels as well as comparable gingival fluid volumes. The glucose content of both the gingival fluid and the blood of the diabetics was significantly elevated above those seen in the control group. The glucose content of the gingival fluid from the diabetics also showed a significant correlation to blood glucose levels found in each patient. The increased glucose content of the gingival fluid in diabetics may reflect metabolic changes in the gingival tissues as well as altered vascular permeability of the capillaries present in the gingival crevice.

Obesity, impaired glucose tolerance, type 2 diabetes, hyperlipidemia, hypertension, and insulin resistance are wellknown components of metabolic syndrome and are associated to increased cardiovascular morbidity. The present study aimed to evaluate the relationships between cardiorespiratory fitness, body fat distribution, and selected coronary heart disease risk factors. A total of 22 untrained subjects affected by one or more features of metabolic syndrome and without clinical history of cardiovascular disease were studied. Nondiabetic subjects underwent an oral glucose tolerance test for glucose and insulin measurement; fasting glucose and insulin were measured in diabetic patients. Complete lipid profile, thyroid hormones, and thyroid-stimulating hormone were measured in all subjects. Basal energy expenditure and cardiorespiratory fitness were measured using a K4 analyzer. Cardiorespiratory fitness ( VO(2max)/kg) was assessed using a treadmill graded exercise test. Peak aerobic capacity ( VO(2max)/kg) was predicted by body fat distribution, insulin sensitivity index, and high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol ( p<0.001). A significant relationship was found between cardiorespiratory fitness ( VO(2max)/kg) and body mass index (BMI), insulin sensitivity index, and LDL cholesterol ( r=0.60, p<0.05; r=0.66, p<0.01 and r=0.54, p<0.05, respectively). Data demonstrated that aerobic fitness is related to metabolic parameters and to body fat distribution, and suggest that its modification may improve well-known predictors of coronary artery disease.

Because of the greater loss of clinical attachment around implants placed in patients with generalized severe chronic periodontitis, close monitoring of these patients is suggested to prevent both development of peri-implantitis and recurrence of periodontal infection.