Lipid-based drug delivery nanoparticles, including non-lamellar type, mesophasic nanostructured materials of lyotropic liquid crystals (LLCs), have been a topic of interest for researchers for their applications in encapsulation of drugs...

Biopolymeric nanoparticulate systems hold favorable carrier properties for active delivery. The enhancement in the research interest in alginate formulations in biomedical and pharmaceutical research, owing to its biodegradable, biocompatible, and bioadhesive characteristics, reiterates its future use as an efficient drug delivery matrix. Alginates, obtained from natural sources, are the colloidal polysaccharide group, which are water-soluble, non-toxic, and non-irritant. These are linear copolymeric blocks of α-(1→4)-linked l-guluronic acid (G) and β-(1→4)-linked d-mannuronic acid (M) residues. Owing to the monosaccharide sequencing and the enzymatically governed reactions, alginates are well-known as an essential bio-polymer group for multifarious biomedical implementations. Additionally, alginate’s bio-adhesive property makes it significant in the pharmaceutical industry. Alginate has shown immense potential in wound healing and drug delivery applications to date because its gel-forming ability maintains the structural resemblance to the extracellular matrices in tissues and can be altered to perform numerous crucial functions. The initial section of this review will deliver a perception of the extraction source and alginate’s remarkable properties. Furthermore, we have aspired to discuss the current literature on alginate utilization as a biopolymeric carrier for drug delivery through numerous administration routes. Finally, the latest investigations on alginate composite utilization in wound healing are addressed.

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Chondroitin sulfate (CS), a natural anionic mucopolysaccharide, belonging to the glycosaminoglycan family, acts as the primary element of the extracellular matrix (ECM) of diverse organisms. It comprises repeating units of...

In this study, we developed a carbon-dot-based sensor, which is particularly sensitive to ascorbic acid. It was possible to generate carbon dots (CDs) by utilising a renewable resource: Curcuma longa, which is abundantly available. The carbon dots produced from curcuma longa have particle diameters of 0.6 nm and are extremely brilliant in appearance. It has been proven that the fluorescence of carbon dots is inhibited in the presence of dopamine and ascorbic acid, with dopamine being more sensitive to the fluorescence than ascorbic acid. There were no significant differences between the minimal detection limits for dopamine and ascorbic acid, which were 33 μM, respectively. The Stern-Volmer plot was used to establish the quenching of ascorbic acid. It is one of the potential technique for sensing ascorbic acid.

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Patients must take significant doses of drugs to acquire the therapeutic effects required for disease therapy due to the absence of selectivity and accessibility of medicinal molecules. Drugs contain a range of drug carriers that are available to transport therapeutic chemicals to the targeted issues in the body. Mesoporous materials are choice for overcoming the aforementioned issues and producing effects in a predictable and long-term way. Because of its chemical characteristics, thermal stability, & biocompatibility, mesophoric nanoparticles are commonly utilized as release reagents. The innovative silica mesophore technology allows for efficient drug loading and administration after the target site has been reached. The additives used to manufacture MSNs can affect the property of mesoporous materials, including pore width, porosity, drug load, and surface characteristics. The need for an active surface provides for surface treatment as well as the coupling of therapeutic substances. They are widely employed in the bio-medical industry for diagnosis, target medication administration, bio-sensing, cellular absorption, and so on. The purpose of this study is, to sum up the existing level of information about mesoporous nanomaterials and their applications in diverse healthcare sectors.

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