Gout Arthritis adalah penyakit akibat kelainan metabolisme asam urat yang tinggi yang disebut hiperurisemia. Prevalensi Gout Arthritis di Indonesia 1,6-13,6 per seribu penduduk. Hiperurisemia disebabkan oleh produksi asam urat yang meningkat dan ekresi asam urat yang rendah. Diet purin adalah salah satu faktor yang menurunkan kadar asam urat. Tujuan penelitian ini adalah untuk mengetahui hubungan antara diet purin dengan kadar asam urat pada penderita Gout Arthritis. Jenis penelitian adalah deskriptif analitik dengan pendekatan Cross Sectional Study yang dilakukan di Wilayah kerja Puskesmas Surian Kabupaten Solok. Populasi penelitian adalah seluruh penderita Gout Arthritis di Wilayah kerja Puskesmas Surian Kabupaten Solok dan sampel didapatkan dengan teknik Accidental Sampling sebanyak 41 responden. Data diolah dengan analisis univariat menggunakan distribusi frekuensi dan analisa bivariat menggunakan uji statistik chi square (α=0,05). Hasil penelitian didapatkan lebih dari separuh (61,0%) responden memiliki kadar asam urat yang tinggi, lebih dari separuh (58,5%) responden memiliki diet purin yang tidak patuh. Terdapat hubungan yang signifikan antara diet purin dengan kadar asam urat (p =0,000).
Diarrhea is a disease that causes sufferers to have frequent bowel movements with watery or watery stools. One of the causes of diarrhea is Escherichia coli bacteria. One of the plants that has been used as an antidiarrheal is guava (Psidium guajava L.), especially the leaves. Guava leaves are known to contain phytochemicals, namely: tannins, flavonoids, alkaloids, saponins, and essential oils which function as antibacterials. This study aims to determine whether guava leaf extract can inhibit the growth of Escherichia coli bacteria. This research is a laboratory experimental study using the paper disc diffusion method (Kirby-Bauer). The sample used was Escherichia coli bacteria obtained from stool samples of diarrhea patients aged 8-12 years at the Nanggalo Health Center, Padang City, West Sumatra Province. The concentrations used in this study were 10%, 15%, 20%, and positive control for amoxicillin and negative control for distilled water. The results showed that the phytochemical test results for flavonoids, tannins and saponins, and alkaloids were positive. The antibacterial activity of guava leaf extract was shown to have inhibition against Escherichia coli bacteria with an average concentration of 10% with a diameter of 10.7 mm (strong), 15% with a diameter of 13.3 mm (strong), and 20% with a diameter of 17 mm (strong). ), 13 mm amoxicillin positive control, and 0 mm negative control. The results of the ANOVA test showed a value of p = 0.000 (sig. <0.05) that there was a significant difference between all treatments with a positive control. It can be concluded that guava leaf extract effectively inhibits the growth of Escherichia coli bacteria, this is because the diameter of the extract inhibition zone is larger than the positive control.
The licensing process of copyrighted materials, especially songs and music for a film, is one of the responsibilities that a producer should fulfill, aside from other responsibilities like financing the film and managing all the needs of the cast and crew. However, the knowledge and awareness about copyright and music licensing are still very low in Indonesia. In this research, the writer will find out about the process of music licensing for a short movie. Through this research, we will look into the music licensing process for film, and national and international film festivals. Keywords: Producer, Music Licensing, Short Movie
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