Abstract-The study aimed to develop critical thinking in chemistry using the Third International Mathematics and Science Survey Questionnaire (TIMSS-Like Test Items) and to lessen or eradicate misconception of students in the scientific concepts. A total of 99 third year Muslim students were selected and grouped into experimental and control group based on their respective section assignment. The experimental group underwent treatment using activity-based learning in a cooperative learning environment, while the control group used only the chalk and board discussions without hands-on. Three instruments were used namely: activities lifted from the TIMSS-R manual, the TIMSS-Like test items, and the selfassessment questionnaire. Both groups are exposed to pre-test and post-test after the conduct of the study. Findings revealed that the experimental group performed better than the control group. Majority of the students in the experimental group realized that the treatment motivated them to think critically. Through hands-on their misconceptions was corrected and lessened. Moreover, they also realized that the activity -based technique in the teaching -learning process is interesting, more fun and encouraging.
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