Central keratopigmentation presented good cosmetic appearance without adverse effects. These results suggest the adequacy of mineral micronized pigments for successful keratopigmentation. The hen animal model is a suitable model for assaying the biocompatibility and tolerance of micronized pigments in central keratopigmentation.
CIC helped on the diagnosis, treatment decision, and follow-up of a patient severely affected by alkali exposure by checking the status of GC in the conjunctiva. Limbal-conjunctival autotransplantation decision was taken and performed consequently, and a significant improvement was observed through a follow-up by CIC.
Purpose To use Conjunctival Impression Cytology (CIC) as a tool for the diagnosis, follow‐up and treatment decision of a patient affected by severe keratoconjunctivitis after exposure to alkali.
Methods A 48 year‐old female patient affected by severe keratoconjunctivitis on her right eye after air exposure to alkali was monitored by CIC. Polyether sulphone filter papers were used to obtain samples from the superior (SB) and inferior bulbar (IB) conjunctiva from the affected eye and stained by PAS‐Giemsa staining to reveal the status of goblet cell (GC) population. After observing a dramatic decrease of GC by CIC, we decided to perform a limbal‐conjunctiva autograft transplantation from the healthy left eye (LE) to the affected right eye (RE).
Results CIC helped in the diagnosis, treatment and follow‐up of a patient affected by severe keratoconjunctivitis after alkali exposure. The decision to perform a limbal‐conjunctival autograft transplantation came after CIC results. This procedure resulted in a significant increase in GC density going from 30 cells / mm2 to 362 cells / mm2 on IB and from 0 cells / mm2 to 430 cells / mm2 on SB conjunctiva of the transplanted right eye, 1 month after the surgery.
Conclusion CIC is a very useful tool for the diagnosis and follow‐up of cases of severe keratoconjunctivitis providing very relevant information about the status of GC and helping with the decision of the treatment to follow.
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