Introduction: Cervical cancer is one of the most common diseases among women, and cause considerable morbidity and mortality. Considering that cervical cancer is an important neoplasia in northeastern Brazil, and the prevalence of high-risk human papillomavirus (HPV) is directly associated with it, this work had aimed to correlate the cytological and/or colposcopic findings with HPV infection status, and verify the performance of MY09/MY11 and GP5+/6+ primers for HPV detection. Material and method: Patients in this study were from Penedo-AL, a city with high level of poverty (poverty rate of 60.62%). Out of 70 patients with cytological and/or colposcopic changes, 32 agreed to participate in the study. Results: Regarding cytology, 21 (30%) patients presented atypical squamous cells of undetermined significance (ASC-US); 20 (29%), atypical glandular cells of undetermined significance (AGUS); 12 (17%), low-grade intraepithelial lesion (LSIL); five (7%), high-grade intraepithelial lesion (HSIL); and 12 (17%), positive colposcopy. From these, 27 (84%) presented the band gene encoding for human ß-globin. From the 27 patients, eight (30%) were positive for HPV. The results showed that the deoxyribonucleic acid (DNA) of HPV was detected in 15% and 30% by using MY-PCR and GP +-PCR, respectively. Conclusion: This study suggests that more than one type of oligonucleotide primer should be used in clinical samples to increase sensitivity for the detection of HPV.
RESUMOPara determinar a prevalência de geohelmintíases de um grupo amostral em Aracaju/SE entre 2007 a 2010, realizou-se busca em arquivos eletrônicos de três laboratórios clínicos do citado município. Nos arquivos se coletou variáveis para determinação de indicadores epidemiológicos. Das 153.912 pessoas investigadas, 49,37% estavam infectadas por algum parasita ou organismo comensal. Entre os geohelmintos, a prevalência foi de aproximadamente 20%, sendo Ascaris lumbricoides o mais prevalente (58,8%). Quanto ao gênero, o masculino foi mais acometido (70,65%), e as faixas etárias mais atingidas foram as de 21anos a 49 anos. Análises mais acuradas dos bancos de dados de Laboratórios de Análises Clínicas podem subsidiar o monitoramento da dinâmica de ocorrência das geohelmintíases e fornecer informações aos órgãos competentes que auxiliem nas tomadas de decisões quanto aos investimentos em saúde, educação em saúde e saneamento básico em Sergipe. PALAVRAS-CHAVE: Prevalência; Helmintíases; Sergipe GEOHELMINTHIASIS: AMOSTRAL PREVALENCE IN ARACAJU (SE) BETWEEN 2007 TO 2010 ABSTRACTTo determine the prevalence of sample group of geohelminths in Aracaju/SE between 2007 to 2010, took place in search of three electronic files of clinical laboratories on the said municipality. Variables are collected in the archives for the determination of epidemiological indicators. Of the 153,912 persons surveyed, 49.37 % were infected by parasite or commensal organism. Among the geohelminths, the prevalence was approximately 20 %, being Ascaris lumbricoides the most prevalent (58.8%). Regarding gender, the male was more affected (70.65%), and the age groups most affected were those of 21 years to 49 years. More accurate analysis of the databases laboratory of clinic analysis can support monitoring of the dynamics of occurrence of geohelminths and provide information to relevant bodies to assist in making decisions about investments in health, health education and sanitation in Sergipe.
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