Infants with perinatal asphyxia have a significantly higher urinary UA/Cr ratio. This may be used as an indicator of the severity of perinatal asphyxia.
Reliability and validity of biparietal diameter (BPD) compared with head circumference (HC) measurement as an index of cranial growth was assessed. A significant correlation between BPD and HC (r = 0.857; p less than 0.0001) and an interobserver reliability of 92% were found. Infants' age and sex had independent effects on BPD growth rate. Very sick infants had a lower increase in BPD rate than healthy controls. It is suggested that in sick premature infants, when the head is encumbered by various types of apparatus, this technique might prove more feasible than HC measurement.
300mg/m 2 /dose TDS regime. Its optimal duration (6months, 12months or longer) is unclear. Neurodevelopmental outcomes mostly depend on the severity of the initial insult; Evidence that different suppressive treatments influence outcomes is poor.
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