BACKGROUND Spongiotic dermatitis is a common diagnosis in routine dermatopathology practice. Clinically it includes eczema and its clinicopathological variants. The main purpose of a biopsy in such cases is to come to a precise diagnosis. We wanted to study the different histopathological features commonly seen in spongiotic dermatitis. METHODS This is a cross sectional study conducted at a Government Medical College in Kerala, South India. All lesions reported as cases belonging to the category of spongiotic dermatitis during the one-year period were included in the study. Patients who presented with an established diagnosis of spongiotic dermatitis were excluded from the study. The study included 41 skin biopsies. RESULTS The age distribution pattern revealed that the highest percentage was in the 10 - 20 years age group (21.95 %) with a male preponderance (68.29 %). Small plaque parapsoriasis was the most common lesion (24 %) encountered in the study. CONCLUSIONS Some of the histopathological features are specific and characteristic for each entity like small plaque parapsoriasis, pityriasis rosea and erythema annulare centrifugum whereas some features overlap in lesions like irritant contact dermatitis and photoallergic contact dermatitis. Therefore, clinical history combined with microscopic features will help us render a precise diagnosis. KEYWORDS Spongiotic, Dermatitis, Inflammatory, Histopathological
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