Cannabis sativa has been reported that it is a widely spread species all over the world. It has been receiving more attention due to its therapeutic potential. Popularly, it is also known as marijuana. The phytoconstituents and characteristics of Cannabis sativa, stem, leaves and seeds were provided with more information in feed materials for its utilization and nourishment. Positive biological activities and pharmacological aspects provided from Cannabis sativa. Cannabis played a key role as a medicinal plant in the lives of tribal people mostly living in the Himalaya, providing products for both food as well as their medicinal purposes. The role of cannabis for treating several medicinal conditions increased day by day. The present paper is reviewed on phytoconstituents and medicinal importance of Cannabis sativa which is mainly aimed at researching the state of the art, and enhancing the knowledge of this versatile plant. Cannabis sativa is from the Cannabaceae family, which is mostly able to live in temperate as well as tropical regions. It is the most commonly used psycho-active drug all over the world and the only one most popular illegal drug. This review mainly analyzes the botanical, descriptional and diversity along with the medicinal importance of marijuana among the human being which is found throughout the worldwide.