Background: Pharmacists are furnished with expert drug knowledge and have been considered as valuable resource of drug information, therefore, are well positioned to play a leading role in the application of pharmacogenomics (PG) in to clinical practice. This might prevent Chemotherapy related adverse events and improve patient outcomes, despite the ethical, privacy concerns and potential implications of lifelong genetic-data. Methods: This review is to evaluate and digest the various studies on Knowledge, Attitudes and Practice concerning pharmacogenomics among pharmacists and to suggest future research areas. 13 English published studies from 2004 to 2014 were selected. Studies involving Pharmacists of different area of practice and covering research from different continents were selected. Only studies on attitudes, knowledge and practice concerning pharmacogenetics among pharmacists from 2004 to 2014, and research articles published in English were selected. Non-research articles, studies done on general public; studies conducted among other healthcare professionals; studies on genetics of diseases or toxicogenetics were excluded. Results: Knowledge and practice regarding pharmacogenetics among pharmacists were poor despite good attitudes. There was knowledge advancement from 38% in 2005 to more than 50% 2013 in some countries. Some barriers to adoption of pharmacogenomics into patient care and interventional recommendations were highlighted. Conclusion: there is an urgent call for additional training of Pharmacogenomics among pharmacists and to incorporate pharmacogenomics into curriculum of pharmacy schools. Pharmacists and future pharmacists should be trained on how to critically evaluate the use, efficacy, and safety of available pharmacogenetic testing.
Batu Buruk beach has been gazetted as a non-smoking zone by the Minister of Health under the initiative of Terengganu state government via their program known as ‘Terengganu Bebas Asap Rokok’ (TBAR). The smoking bans at Batu Buruk was enforced in order to preserve and protect the public from the dangers of cigarette smoke as well as to keep the city's environment clean and healthy. The objectives of this study were to assess the status of compliance to legislation and identify the potential aspects of violations in Batu Buruk, Terengganu, a gazetted smoke-free area. A cross-sectional study using direct observation was conducted includes all indoor and outdoor public areas in Batu Buruk Beach. Data were collected using a standard checklist which was constructed based on the provisions of the law governing exposure to tobacco smoke as stated in Control for Tobacco Products Regulation (CTPR) 2004. The study revealed that the average overall compliance with smoke-free policy was low (66.2%). The average compliance for indoor (67.4%) was higher as compared with outdoor (58.9%). Thirteen smokers were discovered smoking outdoor in the area during the study. None of the owners provides smoking aid at their premises. Although the beach has been gazetted as a non-smoking zone for more than two years, it is disappointing that overall compliance was still minimal and smoking activities are still happening in the area. Along with intense health promotion activities, continuous enforcement, close monitoring and periodic evaluation would improve and ensure the successfulness of the programme.
Spontaneous heterotopic pregnancy is a rare condition. There is the simultaneous presence of intrauterine and extrauterine pregnancies. Such condition can be a life-threatening. The diagnosis can also be easily missed especially in early pregnancy. We present this case of a 28-year old patient who was misdiagnosed as normal intrauterine pregnancy. She had illegal termination of unwanted 14-week pregnancy in a private hospital. The patient presented to us with acute abdomen two days after D&C. Following clinical examination, uterine perforation was suspected. Abdominal ultrasound showed a coexisting abdominal pregnancy in the right hypochondrium. his heterotopic pregnancy was undiagnosed at her initial presentation to the first hospital. Emergency laparotomy was done, uterine perforation was sutured and abdominal pregnancy was excised.
Secondhand smoke (SHS) carries many health risks and is associated with diseases and premature deaths among nonsmoking adults and children. Despite many health promotions and legislative measures executed by the government to protect the public from SHS, the prevalence of SHS exposure is still high. Personal appropriate practices to avoid exposure are crucial especially at home or private area. Therefore, the current study focused on describing individual preventive practices on SHS and determining its associated factors. A cross sectional study was conducted among 250 adults in a village, Kuala Terengganu. Data were collected using self-administered questionnaires. Multiple logistic regression analysis was performed to determine the association between all independent variables and the SHS preventive practice status. The prevalence of SHS exposure was 66.0%. Majority of the respondents (77.2%) has good knowledge on SHS. Nevertheless, despite having good knowledge, a large proportion of them showed poor attitude toward SHS (77.6%) and poor preventive practices (61.2%). Poor preventive practices on SHS were significantly associated with being older (ORadj: 1.0206, 95% CI: 1.0004, 1.0412), female (ORadj: 2.0644, 95% CI: 1.0753, 3.9635), smoker (ORadj: 12.1107, 95% CI: 4.0630, 36.0991), not having existing tobacco-related morbidity (ORadj: 3.6795, 95% CI: 1.1795, 11.4786), and poor attitude towards SHS (ORadj: 4.1871, 95% CI: 2.0955, 8.3665). The preventive practices of SHS among the villagers were poor despite showing acceptable level of knowledge. Hence, health awareness on the potential impact of SHS to the public as well as instilling appropriate behavior for them to avoid SHS and educate smokers need to be emphasized.
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