Schistosomiasis remains a health problem in Central Sulawesi and an intervention is needed to eliminate the disease. Health education training has been carried out to improve knowledge on schistosmiasis prevention and transmission among elementary school children and teachers. The training targets are expected to be an agent of change to introduce schistosomiasis control measures. This study used a quasi-experimental design by providing training materials on schistosomiasis control and followed by collecting and examining stool samples, catching and examining rats, conducting snails survey and examining snails to determine cercaria presence. There were 63 elementary school children participating in the intervention as case group and there were 63 elementary school children in the control group. Structured tests were conducted to determine the improved knowledge of the participants after the health education training within three phases. The results of this research reveal that there is significant improvement on the knowledge in the intervention group and in all post-test, with p-values of 0.000. On the contrary, there is no differences between before and after health education training (p-value=0.356) in the non treated group. It can be concluded that knowledge on schistosomiasis control increases among school community after intervention.
Background: Heart failure is a progressive health problem with high mortality and morbidity rates in developed as well as developing countries including Indonesia. Dapagliflozin is one of the oral antidiabetic medicines of the class of sodium-glucose cotransporter-2 (SGLT2) inhibitors, used in people with type 2 diabetes mellitus (DMT2). Unlike other oral anti-diabetes that work to stimulate insulin secretion or increase insulin sensitivity, dapagliflozin works in the kidneys by competitively inhibiting the SGLT2 protein reversibly which serves in glucose reabsorption in the glomerulus thereby lowering blood sugar levels in T2DM patients. This study aimed to determine the estimated effect of dapagliflozin on the severity of heart failure patients. Subjects and Method: This study was a systematic review and meta-analysis with PICO. Popula-tion= Heart failure patients over 18 years old. Intervention= administration of dapagliflozin. Com-parison= Placebo. Outcome= severity of Heart Failure. The articles used PRISMA flowchart guidelines. The article search process was conducted from 2019 to 2022 using databases from PubMed, Google Scholar, and Scopus with the search keywords Dapagliflozin, Heart Failure, and Placebo. The analysis was performed using RevMan 5.4 software. Results: A total of 8 articles from across 2 continents, America and Asia, reviewed in the metaanalysis, showed that administering Dapagliflozin could reduce the risk of heart failure severity by 0.99 units compared to without dapagliflozin, however, it was statistically insignificant (OR= 0.99; 95% CI= 0.92 to 1.06; p= 0.710). Conclusion:The administration of Dapagliflozin lowers the risk of heart failure severity and is statistically significant.
ABSTRACT Soil-Transmitted Helminths infection is still remain become a health problem in tropical and sub-tropical countries, one of which is Indonesia. The aim of the study was to determine the STH infection in Banawa and Dampelas sub-districts, Donggala district, Central Sulawesi Province. The study was conducted in February - November 2017 on 153 elementary school students. The collected feces were examined by the direct examination method. The results found infections of Ascaris lumbricoides, hookworm, and Trichuris trichiura. We also found Enterobius vermicularis and mixed infections. However, the logistic regression test showed there was no relationship between taking deworming medication and the incidence of worms in school childrenin Donggala Regency (p-value > 0,05). Based on the results it can be concluded that the prevalence of STH infection in both locations is still high. It is necessary to make efforts to treat school children and counseling on clean and healthy living behavior. ABSTRAK Infeksi Soil Transmitted Helminths masih menjadi masalah kesehatan di negara tropis dan sub tropis, termasuk di Indonesia. Tujuan penelitian adalah untuk menentukan tingkat infeksi STH pada siswa sekolah dasar (SD) wilayah Kecamatan Banawa dan Dampelas, Kabupaten Donggala, Provinsi Sulawesi Tengah. Penelitiandilakukan pada bulan Februari - November 2017 dengan jumlah sampel 153. Tinja yang terkumpul diperiksa dengan metode pemeriksaan langsung. Hasil penelitian ditemukan infeksi cacing gelang (Ascaris lumbricoides) cacing tambang (Hookworm), dan cacing cambuk (Trichuris trichiura). Selain itu ditemukan infeksi Enterobius vermicularis dan infeksi ganda. Namun uji logistic regression menunjukkan bahwa tidak ada hubungan antara minum obat cacing dengan kejadian kecacingan pada anak sekolah di Kabupaten Donggala (p-value > 0,05).Berdasarkan hasil penelitian dapat disimpulkan bahwa prevalensi infeksi STH di kedua lokasi masih tinggi. Perlu dilakukan upaya pengobatan anti cacing pada anak sekolah serta penyuluhan perilaku hidup bersih dan sehat.
BACKGROUND: Small mammals such as rats and bats are important animal reservoirs of various zoonotic diseases of public health importance. The potential of rats and bats as a reservoir of leptospirosis and Japanese Encephalitis (JE) in Muna Regency remains unknown. This study aimed to determine the presence of Leptospira spp and JE virus (JEV) in rats and bats in Muna Regency, Southeast Sulawesi Province. METHODS: A cross-sectional survey was carried out in three districts, namely Kabawo, Batalaiworu, and Katobu. Bats and rats were caught in six ecosystems spread across the three districts. Serological (Microscopic Agglutination Test, MAT) and molecular examinations (Polymerase Chain Reactions, PCR) were performed to detect Leptospira spp. and JEV in rats and bats, respectively. RESULTS: A total of 137 rats from seven species were successfully caught, namely Mus sp., Rattus argentiventer, R. nitidus, R. exulans, R. hoffmanni, R. norvegicus, and R. tanezumi. Of which, six species were confirmed positive for Leptospira spp by PCR, with the highest prevalence was found in R. argentiventer (50%) and R. tanezumi (36.4%). Meanwhile, a total of 86 bats were also successfully captured. The JEV antibody was detected in D. viridis, R. celebensis and S. wallacei. CONCLUSION: Rats and bats are the potential reservoirs of leptospirosis and JE in Muna Regency. Most importantly, the study provides the first evidence of JE reservoirs (R. celebensis and S. wallacei) in Sulawesi. Surveillance of leptospirosis and JE are recommended.
Abstract Schistosomiasis in Indonesia has been found in three endemic areas of Central Sulawesi Province and its control program has long been implemented for more than 35 years, but the transmission has remained unchanged. A new integrated and community based strategy, namely “Bada”was implemented in Lengkeka Village.in 2019. The study aimed to determine the impact of the implementation of Bada model to control schistosomiasis using mixed methods. The Bada model consisted of four actions, namely design of village regulations, formation of schistosomiasis control team, the improvement of capacity for several key persons and integrated schistosomiasis control with various sectors. The results showed the increase of stool collection coverage from 54.59% in 2018 to 71.92% in 2019 and the mass drug administration coverage, from 53% in 2018 to 86.04% in 2019. The snail focci areas were reduced from five to three areas. The schistosomiasis prevalence in human was 0% in 2019. The study also found the increasing of the knowledge, attitude, and practice about schistosomiasis and its prevention of people in the study area.. Based on the results, the Bada model can be considered to be implemented in other schistosomiasis endemic areas, with regard to the local wisdom. Keywords: Schistosomiasis, community empowerment, development of Bada model, Lengkeka, Poso Abstrak Schistosomiasis di Indonesia ditemukan di Provinsi Sulawesi Tengah dan upaya pengendalian sudah dilakukan selama lebih dari 35 tahun terakhir, tetapi sampai saat ini penularan masih terjadi. Sebuah strategi baru pengendalian schistosomiasis terintegrasi dan berbasis masyarakat, yang disebut pengembangan model “Bada” diimplementasikan di Desa Lengkeka tahun 2019. Penelitian dilakukan dengan mixed methods Pengembangan tersebut terdiri atas empat kegiatan, yaitu penyusunan peraturan desa, pembentukan tim pengendalian Schistosomiasis desa/Tim Peda’, peningkatan kapasitas dalam pengendalian schistosomiasis melalui beberapa tokoh masyarakat dan program pengendalian Schistosomiasis terintegrasi lintas sektor. Hasil implementasi menunjukkan terjadi penurunan kasus schistosomiasis pada manusia dan hewan mamalia ternak menjadi nol, meningkatkan cakupan pengumpulan tinja manusia, dari 54,59% menjadi 71,92%, juga meningkatkan cakupan pengobatan dari 53% pada tahun 2018 menjadi 86,04% pada tahun 2019. Pengembangan Model Bada dapat menurunkan jumlah daerah fokus dari 5 menjadi 3 daerah fokus, juga menambah pengetahuan, sikap dan perilaku masyarakat secara signifikan. Berdasarkan hasil tersebut Pengembangan Model Bada dapat dipertimbangkan untuk diimplementasikan di daerah endemis schistosomiasis lain di Provinsi Sulawesi Tengah, dengan tetap mempertimbangkan kearifan lokal masingmasing desa. Kata kunci: Schistosomiasis, pemberdayaan masyarakat, pengembangan model Bada, Lengkeka, Poso.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.