No abstract

Advanced glycation end products (AGEs) are glycated proteins associated with high dry temperature food processing, coloring and flavor modification of food products. Previous studies on diet-related disease support the role of the glycation products as biomarkers in local and general proinflammatory response. Exogenous and endogenous AGEs are involved in chronic low-level inflammation, which underlies the onset of metabolic syndrome influenced by food intake, there by demonstrating their implication in diet-related pathologies. Although studies have revealed a strong association between the accumulation of AGEs and the occurrence/worsening of metabolic diseases, their routine use for the diagnosis or monitoring of local and general disease has not yet been reported.

In oral rehabilitation, the treatment of partial edentulism (PEd) is performed by removable partial dentures (RPD) or assembled prosthetic works (APW) composed of several components, fixed to the prosthetic field (Pa) and a removable one (Pb), in order to facilitate the daily hygiene but also the damping of the occlusal forces applied in mastication. Cobalt-Chromium alloys are materials used to manufacture modern prosthetic assembles. In order for this study to be relevant, it was necessary to standardize the design of the framework (Pa) in terms of shape and volume so that the experiment could be reproducible for the five Co-Cr alloys: 0-A (Co-Cr-Mo), 5-A and 10-A (Co-Cr-Mo-W), 15-A and 16.4-A (Co-Cr-W-Fe) and for the three fabrication methods of dental assembled prosthetic frameworks: refractory duplicate method (RD) resulting removable framework (Pb), direct construction method (DC) resulting removable framework (Pb-) and casting over metal method (CoM) resulting removable framework (Pb+). The time allocated to the adaptation process (AP), mechanical processing and sandblasting, in order to assemble the two components was between 43–70 min, even though the assembly between the Pa-framework and the complementary framework (Pb+) was not necessary, CoM-method hs been provide the elimination of AP step. By applying the arithmetic simple rule of three, the percentages for each of the three methods used were calculated, the values of the difference were obtained. The CoM method improves the joining precision between the components of the removable assembly of prosthetic frameworks by 91.7% compared to the RD method and by 80.62% compared to the DC method. According to the efficiency of the methods used in the precision of joining between frameworks components, their order is: casting over metal, direct construction and refractory duplicate method.

No abstract

Clinical manifestations of human papillomavirus (HPV) infection in the head and neck can range from benign lesions, which are the most frequent, to malignant lesions. The prevalence of head and neck cancer is increasing, despite currently decreasing trends in known risk factors such as smoking and alcohol use. A new patient profile has appeared in recent practice: most frequently a middle-aged male patient who does not smoke or drink alcohol, is sexually active (possibly having multiple partners), and presents with oral or cervicofacial lesions requiring diagnosis and treatment. Another risk factor that should be considered in these patients is HPV infection. The association of oral potentially malignant disorders (OPMD) with HPV is a challenge for the medical practitioner. The gold standard for diagnosis is histopathological examination, which can also yield evidence suggesting HPV infection. Determination of the viral genotype provides additional data for assessing the oncological risk of an HPV infection. Treatment of these patients is aimed at removing the lesions, in association or not with antiviral treatment and recurrence control.