Pseudomembranous colitis and co-trimoxazolePseudomembranous colitis is associated with antibiotic treatment. We report here its first published link with co-trimoxazole.
Case reportAn 80-year-old woman was admitted to hospital with a fractured neck of the femur, which was managed by internal fixation. Antibiotic cover was not provided for the operation. On the sixth day after operation she developed a fever, which was clinically attributed to a urinary infection, although no organism was subsequently cultured. Treatment was started with cotrimoxazole (Septrin), two tablets twice daily. On the 15th day after operation the patient developed offensive diarrhoea, but the co-trimoxazole was not discontinued until the 20th day. Culture of the stool showed no pathogen,
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