Development trends need the necessity for wider use of the local resources and available natural materials are one of the priorities around the world. Freshwater sapropel is a common material in the water basement of the lakes, but still not sufficiently explored. The main goal of the project to start detailed and systematic research on the medical properties of sapropel to be obtained in Latvia, promote its scientifically based use in balneology, develop new medical procedures and services, and promote development of new exportable products. The results include the survey, sampling depths, and processing, evaluation of external signs, physical, chemical, and biochemical parameters, and evaluation of microbiological indicators. Active components from the sapropel samples extracted using the alkaline method. Sapropel extracts were characterized by organic carbon content, humic and fulvic acid concentrations, total phenolic content, trace metal and pesticide concentrations, total antioxidant status, and microbiological flora. Summarizing the article's main findings it was concluded that Latvian freshwater sapropel can be used as raw material for obtaining sapropel extract and use it in the preparation of pharmaceuticals and promote the development of new exportable products and services.
While many people work remotely during the pandemic, three-dimensional (3D) printers are working to ensure the medical personnel and general public with the necessary specific materials. Ease of use, low cost, fast prototyping, and a wide range of materials are the advantages of 3D technology that can quickly adapt to specific needs in different application areas and result in increased popularity. The aim was to analyse the concentrations of particulate matter (PM) and volatile organic compounds (VOCs) emitted in 3D printing zone where printers are located throughout the room around the perimeter and where orthopaedics and designers develop models during their full shift. The average ultrafine particles (UFP) concentration level fluctuates from 4×103 to 26×103 particles/cm3 that exceed the background level (<3×103 particles/cm3) during 8 h-shift. Microclimate was evaluated as unsatisfied regarding permissible values for air quality at workplaces: air temperature exceeds permissible upper level +25 °C, relative humidity was 21.5 % and air velocity ≤0.05 m/s. The highest particles’ number concentrations in the nano-scale range (<0.1 μm) and significantly higher mass concentrations in the coarse particle range (>2.5 μm) were detected. The median diameters of particle number (0.019, 0.014, 0.015 μm) and mass concentrations (4.394, 4.433, and 4.677 μm) were similar in all observed premises. Total VOC concentration was increased and specific substances such as toluene and formaldehyde (0.56±0.1 and 0.23±0.034 mg/m3) were found at high concentration in comparison with indoor air quality recommendations.
Found in lakes, freshwater sapropel is a sediment with a fine structure containing more than 10% of organic matter as well as residues of aquatic organisms with a small content of inorganic components of biogenic origin and mixture of mineral ingredients. The mud was first used in medicine by ancient Greeks, and it gained more popularity together with development of balneology in Europe in the 19th century as a remedy for several diseases. The last century also brought wider popularity in its cosmetic use. Despite its wide usage, mechanisms behind its effects are not so clear yet. Broad but fragmented studies on the effects of sapropel are available, but few have used modern research methods. There is evidence suggesting that its positive health effects are linked to its thermal capacity, ability of penetration in tissues and biological activity of its components, e.g., humic substances. Evidence also suggests antimicrobial activity and positive effects on skin regeneration. This review aims at summarising available knowledge on the structure and composition of sapropel and its effects on the human body, as well as its potential for further evidence-based use in medicine and cosmetics.
Previously, sapropel has been commonly used in agriculture, cosmetology and medicine in its raw form and there has been no generally accepted method or standard for realizing sapropel extract. However, for sapropel usage in medicine, balneology and pharmacy, it is essential to develop quality criteria for raw sapropel and its extracts. This review aims at discussing and summing up different techniques for extracting bioactive compounds from sapropel as well as the possibilities of creating quality criteria. This paper covers existing analytical techniques and methodologies; currently, there are few extraction methods using several extractants for obtaining bioactive components from raw sapropel. Different freshwater sapropel types have been described and characterized. Bioactive components in sapropel have been identified and explained. Humic acids and fulvic acids have been identified as the main substances and their extraction methods have been listed. Solid-liquid, ultrasound assisted and supercritical fluid extraction methods have been pointed out as the most suitable. Additionally, analysis and storage conditions of the extracts have been discussed. There have been found to be no commonly accepted standard methods for sapropel extraction, or for the analysis and characterization of the sapropel extracts. For pharmacological applications, a common approach for the extraction process of active substances from sapropel and the analysis procedures of the extracts need to be established. This review will help equip other researchers with the latest information on this topic.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.