The BVOA-CHR offers a novel framework for the prospective studies on THR and on a national/international scale. Initial complication rates from the BVOA-CHR are similar to previous studies.

General rightsThis document is made available in accordance with publisher policies. Please cite only the published version using the reference above. Full terms of use are available: http://www.bristol.ac.uk/pure/about/ebr-terms and report owner-assessed outcomes.Methods: Entries into the British Veterinary Orthopaedic Association-Canine Hip Registry (BVOA-CHR) between September 2011 and December 2012 were reviewed separately and in conjunction with previous data. An online, owner-administered outcomes assessment questionnaire (modified from the Liverpool Osteoarthritis in Dogs (LOAD) questionnaire) was used to collect outcomes data from owners. Results:The incidence of surgeon and owner reported complications were 8.2% and 4.3% respectively. No significant association was identified between bodyweight, age, sex, breed or indication for THR and the incidence of complications. THR using the BFX cup/stem prosthesis had a significantly greater likelihood of complication compared to when using the CFX cup/stem prosthesis (p=0.002); a complication was 4.48 times more likely to occur when using the BFX cup/stem prosthesis versus the CFX cup/stem prosthesis. THR using the BFX cup/stem prosthesis had a significantly higher likelihood of complication compared to when using a hybrid prosthesis (BFX cup/CFX stem, CFX cup/BFX stem) (p=0.046); a complication was 2.85 times more likely to occur when using the BFX cup/stem prosthesis versus a hybrid prosthesis. In 95% of cases, owners described their satisfaction with the outcome of THR as 'very good' or 'good'. Conclusions:Complication rates from the BVOA-CHR are similar to previous studies. 'Surgeon' and 'clinic' are not variables in our analysis (contractual) but the data suggest that prosthesis type has a relationship with complication rate, with Biomedtrix BFX (circa 2012) having a high short-term complication rate.

There was a high incidence of AKP, and while the short term prognosis appears relatively good in the majority of cases as reflected in the median TDL, a large minority were medically discharged and held back in training. Further work should examine methods of reducing the disease burden of AKP in the Army, addressing areas such as aetiology, prevention and treatment.

Fetal size was smaller in a rural Indian population than in European and urban Indian populations, even in mid pregnancy. The deficit varied for different fetal measurements; it was greatest for AC and BPD and least for FL and HC.

In this cohort, repeated measurements of risk factors seemed to explain more of the educational gradient in CVD mortality. This suggests that a substantial part of the excess CVD mortality among those with lower education might be explained by conventional risk factors.

Scientific Reports 6: Article number: 39535; published online 23 December 2016; updated on 24 April 2017 The original HTML version of this Article listed an incorrect volume number. This has now been corrected in the HTML version; the PDF version was correct at the time of publication.

No abstract

Objectives: To estimate both the association of surgical variables in complete unilateral cleft lip and palate (cUCLP) in the UK with outcomes at age 5 years, and the association of secondary speech surgery, volume of surgery, and surgeon with the same outcomes. Setting and Sample Population:The Cleft Care UK study, a cross-sectional study of 268 5-year-olds, born from 2005 to 2007, with cUCLP.Materials and Methods: Information on surgical variables was extracted from a standardized questionnaire. Dento-facial outcomes were derived from dental study casts of dental arch relationships. Three speech outcomes -intelligibility, structure and articulation -were derived using the Cleft Audit Protocol for Speech-Augmented tool.Results: Surgical and outcome data were available for 211 (79%) children from all cleft centres in the UK. Later soft palate surgery was associated with a 17% increased chance of a poor intelligibility score (P = .02), and high volume surgery with a 249% increased chance of a good articulation score (P = .01). There were no between surgeon effects identified. No association between the surgical variables examined and dento-facial outcome, or secondary speech surgery by the age of 5 years were found. Conclusion:This study found associations between surgical variables and speech outcomes at 5 years of age, but not between surgical variables and dento-facial outcome, nor between surgical variables and secondary speech surgery. High surgical volume should be maintained, and any changes towards later surgery monitored for changes in speech outcome.