SEASICKNESS is a serious inconvenience to many people in times of peace. In times of war, however, motion sickness in its various forms may be a very real threat to the success of operations in the air and on the sea. Army personnel are apt to be affected in very large numbers, when airborne or in landing craft, since they have little opportunity to become acclimatized, as does the sailor or the airman.The literature on motion sickness up to 1942 has been reviewed elsewhere.1 Since that time a large amount of important work has been done, but publication has been in restricted reports. It is hoped that various workers will soon write up their results for open publication.The present paper is a summary of studies carried out during the recent war by a group of workers in Montreal of which we were a part. These experiments on the mechanism of motion sickness were made at an early stage of the investigation in the hope that they might give a lead to specific therapy. Later, through urgency, all our attention was devoted to therapeutic experiments. It is probable, however, that if worth while advances are to be made in therapy more must be known of the fundamental mechanism of motion sickness. MATERIALS AND METHODSMany hundreds of human volunteers were subjected to various types of motion.The majority were naval ratings from H.M.C.S. Montreal, but University students and members of the staff of the Montreal Neurological Institute also volunteered.The device first used was designed to reproduce the wayward movements of a ship at sea.
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